Hi list members,

Is there an effective way for extracting sequence from human genome hg19 by
coordinates?
i have millions of start-end positions, might this huge amount of data not
suite for Table browser.
I was think use the .2bit genome, any suggestions?
i am also thing using following steps:

**

* *

*twoBitToFa*
*

twoBitToFa - Convert all or part of .2bit file to fasta

usage:

   twoBitToFa input.2bit output.fa

options:

   -seq=name - restrict this to just one sequence

   -start=X  - start at given position in sequence (zero-based)

   -end=X - end at given position in sequence (non-inclusive)



faToNib

faToNib - Convert from .fa to .nib format

usage:

   faToNib in.fa out.nib



nibFrag

nibFrag - Extract part of a nib file as .fa

usage:

   nibFrag file.nib start end strand out.fa

Is this would be the fast way?

Thanks in advance.

Best.
*

-- 
Daofeng Li
Postdoc Research Associate
Department of Genetics
Washington University in St.Louis School of Medicine
314-556-2832
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