Hi Assaf,

Our engineer had this to say:

".lav files are only for pair-wise alignments, only two genomes. The
MAF files have all the genomes in the multiple alignment."

We recommend that you use this program: mafsInRegion which can be
obtained from the kent source tree. Information about all of the
utilities can be found at:
http://genomewiki.ucsc.edu/index.php/Kent_source_utilities

Information on how to obtain the source:
http://genome.ucsc.edu/FAQ/FAQlicense.html#license3.

If you have further questions, please contact the mailing list:
[email protected].

Vanessa Kirkup Swing
UCSC Genome Bioinformatics Group


---------- Forwarded message ----------
From: asas asasa <[email protected]>
Date: Thu, Aug 25, 2011 at 4:02 PM
Subject: [Genome] mapping the chromosomal coordinates of one species
to other species
To: [email protected]


Hi all,

I would like to build a script that gets start/end chromosomal coordinates
of specific species, and rapidly finds the homologous coordinates and
strands from other species, or to use such function/program
if already exists (maybe in the Jim Kent's source code ?).
But, it is important for me to get the coordinates in the maximum bp
resolution (as the alignment include gaps, I would like to know where they
are located).

Basically, the Multiz alignments in the MAF format, store such information,
but I'm wondering if there is an efficient way to extract
this information from the files, or from similar files. In addition,
the Multiz files are huge, and I'm looking for a more compact storage
if exists (e.g., http://www.bx.psu.edu/miller_lab/dist/lav_format.html ).

Best wishes, and thanks in advanced for any relevant help,
Assaf
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