Hi Volkhard,

I just wanted to follow-up with some additional guidance.

To use a bigBed file for a custom track, it cannot be compressed; so, if 
your file is compressed (.bz2) you'll need to uncompress it.

Also, when creating a custom track with a bigBed file, you don't submit 
the actual file to us. Instead, you first move your bigBed file 
(myBigBed.bb) to a http, https, or ftp location. Then you create a singe 
track line that provides the location of your bigBed file. The most 
basic version of the "track" line will look something like this:

track type=bigBed name="My Big Bed" description="A Graph of Data from My 
Lab" bigDataUrl=http://myorg.edu/mylab/myBigBed.bb

You then paste this track line into the text box of the custom track 
page (http://genome.ucsc.edu/cgi-bin/hgCustom) and submit.

For further information, on bigBed custom tracks see:
http://genome.ucsc.edu/goldenPath/help/bigBed.html

For more information on custom tracks in general, see:
http://genome.ucsc.edu/goldenPath/help/customTrack.html

Please contact the mail list ([email protected]) again if you have any 
further questions.

Katrina Learned
UCSC Genome Bioinformatics Group



On 11/3/11 12:31 PM, Vanessa Kirkup Swing wrote:
> Hi Volkhard,
>
> It is likely that this is issue "Unrecognized format line 1" is the result
> of line breaks in the track line. Please take a look at step 7 on the page
> below:
>
> http://genome.ucsc.edu/goldenPath/help/bigBed.html
>
> All of the information has to be on a single line. Please make sure that
> you have it in the proper format.
>
> If you have further questions, please contact the mailing list:
> [email protected].
>
> Vanessa Kirkup Swing
> UCSC Genome Bioinformatics Group
>
> ---------- Forwarded message ----------
> From: Dr. rer. nat. Volkhard Seitz<[email protected]>
> Date: Thu, Nov 3, 2011 at 12:46 AM
> Subject: [Genome] Problems to up-load large bed files (Internal Server
> Error E 500)]
> To: [email protected]
>
>
> Dear UCSC team
>
> Two days agou I tried today for hours to up-load ChIP-Seq bed-files.
>
> I can upload files up to 200.000 KB
>
> Since I could not up-load a file with 812.136 KB I used now a
> compression method you recomended an created a .gz file with 189.216 KB
> (The filename was: C_Hodg_Ip_Kmh2_.gz)
> The upload of this compressed .gz file caused the internal server error
> 500.
>
> After writing to your team From I got the recommendation to convert my
> file into the Bigbed format.
> http://genome.ucsc.edu/goldenPath/help/bigBed.html
>
>
> The next day I converted a bed file into a bigbed file employing galaxy.
> The original file had a size of 856.831 KB and the converted bigbedfile
> 245.056 kb respectively.
>
> The conversion report from Galaxy sounded fine:
>
>> 13: BED-to-bigBed on data 12 239.3 Mb
>> format: bigbed, database: hg19
>> Info: pass1 - making usageList (25 chroms): 55588 millis
>> pass2 - checking and writing primary data (14673975 records, 6 fields):
>> 141460 millis
>> index write: 28 millis
>> pass3 - writeReducedOnceReturnReducedTwice: 66343 millis
>> further reductions: 9811 millis
>>
> However I still have the up-load problems for the UCSC Browser
>
> I got the following error measages employing different file formats or
> file names (compressed and non-compressed):
>
>
> 1) File 'KMH2MYCIP.bigbed.bz2' - Unrecognized format line 1 of
> somefile.bz2: ëò??  (note: chrom names are case sensitive)
>
> 2) File 'KMH2MYCIP.bz2' - Unrecognized format line 1 of somefile.bz2: ëò??
> (note: chrom names are case sensitive)
> 3) Can't read file: KMH2MYCIP.bigbed
>
> Could you five me other suggestions how I can up-load files.
> Would be really great.
> Thank you and best wishes from Volkhard
>
>
>
>
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