Hey Hong, I'll go ahead and regenerate the alignments for the refSeq gene models. These should be ready by tomorrow. I'll send you some mail off-list to tell you when they're done. In the near future we plan to regenerate these files more frequently. I don't understand your question about NM_001024599 and NM_000344. Those two genes have significantly different mRNA sequence, and are found in different places in the genome. I hope this answers your questions. Please reply to this list with any follow up questions. Brian On Tue, Dec 6, 2011 at 11:57 AM, Hong Lu <[email protected]> wrote: > Hello, > > I am interested in the multiple alignment of human proteins from UCSC. > http://hgdownload.cse.ucsc.edu/goldenPath/hg19/multiz46way/alignments/refGene.exonAA.fa.gz > > But this file is relatively old (about two years old). Are you planing to > update this file? If so, would you please tell me when it can be released. > NCBI has been updated many genes within the last two years. > > And also, when I read that file, I found sometimes the human protein > sequences are exactly same, but the multiple alignment are very different > (such as NM_001024599 and NM_000344). Could you tell me the reason? Thanks. > > Best, > > Hong > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome
_______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
