Hi Sebastian,

One of our engineers commented:

" The rules are not actually as stated. The actual rule is encoded by 
this SQL statement:

select name from refGene where cdsStart != cdsEnd and cdsStart != 
txStart and cdsEnd != txEnd

that is, there has to be a coding portion, and the gene model has to 
have annotated 5' *and* 3' UTR's."


Please let us know if you have any additional questions: [email protected]

-
Greg Roe
UCSC Genome Bioinformatics Group


On 3/5/12 3:16 AM, Sebastian Ohse wrote:
> Hi Greg,
>
> thanks for adding the link. There is one other question I have with
> regards to the provided "upstream1000.fa.gz" file. It mentions in the
> FAQ that only "RefSeq genes that have annotated 5' UTRs" are included.
>
> This is probably because information about the TSS is needed to compute
> the correct upstream sequences. However, what exactly is the criteria
> used to decide if a RefSeq gene has a properly annotated 5' UTR? Is
> there a public database which contains this subgroup or is some UCSC
> pipeline used instead?
>
> Best,
> Sebastian
>
>
>
> On Tue, 2012-02-21 at 13:18 -0800, Greg Roe wrote:
>> Ah, yeah, we try to limit search engines from cataloging our test
>> server, but sometimes things get through.
>>
>> To get to the fold from out home page (http://genome.ucsc.edu), click
>> the downloads link down the left side menu. Then click Human, and then
>> the "Full Data Set" link.
>>
>> Good idea to add a link from that FAQ page. I'll do that today.
>>
>> - Greg
>>
>>
>> On 2/21/12 12:03 PM, Sebastian Ohse wrote:
>>> It comes up in the first results when you goggle for "bigzips ucsc". How
>>> do people normally find the folder? The below reference mentioned it's
>>> in the bigZips download directory but there was no link...
>>>
>>> http://genome.ucsc.edu/FAQ/FAQdownloads.html#download18
>>>
>>> Best,
>>> Sebastian
>>>
>>>
>>> On Tue, 2012-02-21 at 11:52 -0800, Greg Roe wrote:
>>>> Just out of curiosity. How did you end up with a url to our test server
>>>> (hgdownload-test.cse.ucsc.edu)?
>>>>
>>>> - Greg
>>>>
>>>> On 2/18/12 6:21 AM, Sebastian Ohse wrote:
>>>>> Hi,
>>>>>
>>>>> I have a question about the "upstream1000.fa.gz" file in the bigZips
>>>>> directory of the current assembly.
>>>>>
>>>>> http://hgdownload-test.cse.ucsc.edu/goldenPath/hg19/bigZips/
>>>>>
>>>>> It is mentioned in the Readme.txt of the same directory that the
>>>>> "upstream1000.fa.gz" file is updated weekly. However, the date of last
>>>>> modification is displayed as "20-Mar-2009 09:53". Clearly it's old.
>>>>>
>>>>> Further more, a previous post on the mailing list (back form the hg18
>>>>> assembly) mentioned that these download files are only created once and
>>>>> thus anyone requiring an up-to-date version has to create such
>>>>> themselves.
>>>>>
>>>>> https://lists.soe.ucsc.edu/pipermail/genome/2008-December/017777.html
>>>>>
>>>>> Can someone tell me if the information in the Readme.txt is indeed
>>>>> incorrect and that I now have to construct an up-to-date version myself?
>>>>>
>>>>> Thanks,
>>>>> Sebastian
>>>>>
>>>>>
>>>>> _______________________________________________
>>>>> Genome maillist  -  [email protected]
>>>>> https://lists.soe.ucsc.edu/mailman/listinfo/genome
>
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