Steve,

try glusterfs 3.3 and look at: 

http://community.gluster.org/a/linux-kernel-tuning-for-glusterfs/

There will be more optimizations in the next Gluster release.  Take advantage 
of the translators that Gluster supplies, including readahead translator and 
quick-read translator.

Red Hat does offer support for Red Hat Storage based on Gluster, and it has a 
pre-packaged tuning profile built into it.   We test with 10-GbE networks and 
Gluster 3.3 does have reasonably good performance for large-file sequential 
workloads (and it's scalable).
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