vidhya sankar wrote:
Dear justin,
Very very Thank you for witty and useful reply.
I would like to study the effect of ionic strength on protein stability
Through SMD is it possible ? Can i correlate the result of SMD with
stability ?
Because at high ionic strength The H-bonding between chains is
disrupted only hydrophobic interaction exists?
SMD is a roundabout way to look at this. At sufficiently high ionic strength,
the protein may be destabilized in the absence of an applied force.
-Justin
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========================================
Justin A. Lemkul
Ph.D. Candidate
ICTAS Doctoral Scholar
MILES-IGERT Trainee
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
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