Quite a lot has been done on the privacy model and how to apply it.
Here is a BMJ editorial: http://bmj.bmjjournals.com/cgi/content/full/312/7039/1112
it points to the Anderson principles at http://bmj.bmjjournals.com/cgi/content/full/312/7023/109at least one partial implementation of those principles exists, in closed source.
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