Journals with 90% rejection rates, like Nature, Science and Cell have considerably higher editorial costs (per published paper) than those with rejection rates of 40%-60%, which is an average value for middle-of-the-road biomedical journals. Nearly the same effort goes into peer reviewing a rejected paper as an accepted paper.
As PLoS charges only those authors whose papers are published, and as they aspire to Nature-like selectivity, their editorial costs will be higher than "average" open-access journals. You might even call their $1,500 a bargain. ---------------------------- Alexander M. Grimwade Ph. D. Publisher THE SCIENTIST 3535 Market Street, Suite 200 Philadelphia PA 19104-3385 Phone: (215) 386 9601 x3020 Fax: (215) 387 7542 Email: agrimw...@the-scientist.com Web Site: http://www.the-scientist.com