Scientists find anti-malarial properties in Goan delicacy
The Times of India
Kounteya Sinha 
Tuesday, March 14, 2006 11:59:48 pm

NEW DELHI: One of Goa's most exotic delicacies could soon lead India's
fight against malaria. 

Scientists from the National Institute of Oceanography in collaboration
with researchers at the National Centre for Cell Science, Pune, and
International Centre for Generic Engineering and Biotechnology have
isolated molecules from the Indian green mussel (perna viridis) that
kills the chloroquine resistant malaria parasite, especially the
Plasmodium falciparum type, very effectively. 

The molecules, named NIO-1 and NIO-2, have been sold to a Mumbai-based
company which will develop and commercialise the anti-malaria drug. 
According to NIO's Anil Chatterji, pre-clinical toxicity study of the
molecules have shown absolutely no side effect. Clinical trials will
begin in two months. The project to find the molecules was funded by
CSIR.

Chatterjee said: "The molecules will be extremely effective especially
against chloroquine resistant strain of malaria parasite - W2Mef. 
The molecules kill the parasite rather than just inhibiting their
growth. Compounds were found to be non-toxic to human cells with no
negative effect seen on them.

~(^^)~

Avelino

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