Are we here to play gotcha on facts and information? Or are we here to dialogue, outline perspectives and arrive through dialogue to consensus opinions and mutual answers? Some may think this is an intrusion into Selma's thread. Nope! Yet, it is similar.
Even more amazing is when one is challenged for information by others. The challengers make no effort to get any facts on their own. And when some do so, and get independent corroborating facts, they do not believe in them either. A good example was the recent brouhaha about the Goan mauxi's kani and the mice experiment. Verdes in his account of Goa's cancer kaneos reteriorated a different version of the mauxi's kani which fundamentally did not differ from mine. Please read his post if needed. The moderators understandably blocked my acknowledgement to that post. I accept their decision. Santosh challenged me (rather harshly) to my facts and kindly sent me about seven references to back his claim. It is clear that he and Dr. Jayant appeared to confuse the issue of excising a single / solitary / primary tumor (take your pick, depending on your technical background); to removing only some tumors in multiple / several / metastatic lung tumors. The detrimental effects of the surgery in the LATTER SITUATION was attributed to depressed immunity. >From the seven references on Santosh's list, two papers appeared relevant >papers. I requested our librarian to retrieve the 1976 paper, titled: Effects > of Surgery on Cell Kinetics of Residual Tumor, by Linda Simpson-Herren et al. >(Cancer Treat Rep 60:1749-1760, 1976). After describing their mice experiments, under RESULTS (pg 1750), the authors report, "The mass of lung tumor in surgery-treated mice appears to approach this (lethal tumor) burden at a more rapid rate that similar tumor masses in the intact - untreated, tumor bearing mice." Under Effects of Surgical Excision (pg 1756), the authors report (with surgery) there is an increase in growth rate (of remaining tumors); and reduction in life span of the surgically treated mice than in controls. In the following paragraph, the authors continue, this "would be entirely consistent with outburst or acceleration of growth of existing tumor foci and may be due, in part to change in the immune status of the host (4 additional references) after removal of the tumor." I thank Santosh for providing the reference which addressed his own questions / concerns / issues or non-issues. I do not plan to read the remainder of the references, because I do not have the time. Neither do their titles suggest that those studies have any bearing on the topic under discussion. There are about 4-5 different explanations why partial surgery in advanced cancer may have a detrimental effect on the remaining cancer. Hope this dialogue stimulated young goanetters into the exciting world of science and research. I do not plan to pursue this discussion any further. Regards, GL _______________________________________________ Goanet mailing list [email protected] http://lists.goanet.org/listinfo.cgi/goanet-goanet.org
