Big Pharma in the US riding on the backs of criminally compliant prescribing 
physicians along with the drug cartels in South America have wreaked 
unimaginable havoc on American lives. 

Here, Al Jazeera in a weekend read has opened up a can of worms:

For years, the American opioid crisis was too big, and too complicated, to see 
in its entirety.

There was the view from communities where people fatally overdosed every day on 
OxyContin, a highly addictive (and highly profitable) pharmaceutical opioid. 
There was the view from the Food and Drug Administration, where top officials 
allowed Purdue Pharma to falsely claim that the product was safe. There was the 
view from law enforcement, which struggled to build durable cases against the 
billionaire-owned company.

And finally, there was the view from the Purdue C-suite, where members of the 
Sackler family – the company’s breathtakingly unscrupulous owners – pushed 
employees to overprescribe their deadly drug while hiding its dangers.

It wasn’t until around 2018, when a spate of lawsuits were unveiled against 
Purdue, that all these perspectives came together. This appalling intersection 
is the terrain covered by Dopesick, an ambitious and exquisitely acted 
eight-part TV series on Hulu that spans the late 1990s to 2019. Based on Beth 
Macy’s book of the same name, it has a star-studded cast.

One of the breakout stars is Kaitlyn Dever, who plays a young queer West 
Virginia coal miner who goes from a “legitimate pain patient” to a full-blown 
addict. The distinction between “pain patient” and “addict” is key both to the 
series and, one realizes while watching the show, to Purdue’s strategy of 
avoiding litigation.

Purdue Pharma revolutionized the field of medical advertising in the 1970s by 
identifying new “problems” that only its drugs could treat. Two decades later, 
the company was hiring pay-for-play doctors to endorse made-up conditions like 
“breakthrough pain” and “pseudoaddiction” to legitimize the overprescription of 
OxyContin.

When reports of the drug’s devastating effects became too loud to ignore, the 
company blamed so-called abusers. Real pain patients, Purdue claimed, just 
couldn’t get addicted.

As Dopesick documents, the company was full of dirty marketing tricks. For 
example, Purdue:
instructed reps to wine and dine doctors and bribe receptionists. 
tied bonuses to pharmaceutical sales and offered top-selling reps trips to the 
Caribbean. 
dumped millions into shell companies and pseudoscientific studies and 
conferences, seeking to redefine pain as something that could be “managed” for 
life (with the help of Oxy, of course).
deliberately rolled out the drug in southwest Virginia, eastern Kentucky and 
rural Maine – areas oriented around coal mining, farming, logging and "places 
where people get injured doing labor-intensive jobs." Within a few years, crime 
rates spiked and so-called pill mills were everywhere. 
did some strategic hiring, including Rudy Giuliani as a political lobbyist, an 
FDA official that vetted OxyContin and an attorney general who had campaigned 
against the drug.
Although the series gets lumpy when it tries to cram all this corruption in, 
the characters in Dopesick are rendered with intimacy and depth (minus the 
Sacklers, whose extreme wealth and emotional chilliness come off as 
cartoonish). Michael Keaton embodies the contradictions and torment of a 
well-meaning doctor who realizes he has been poisoning those in his care before 
becoming an addict himself. Ray McKinnon and Diane Mallum, playing the 
conservative religious parents of the teenage coal miner, are heartbreaking in 
their efforts to save her from the drug that has robbed her of her will to live.

The larger story, of course, isn’t over. Purdue Pharma declared bankruptcy last 
year, and so did the Sacklers (though a judge recently overturned a ruling that 
protected them from individual liability). Meanwhile, the opioid crisis has 
morphed and worsened, with the gap left by the pharmaceutical companies now 
filled by Mexican cartels. Fueled by the pandemic, opioid-related overdoses 
increased by more than 28% last year, hitting an all-time high of over 100,000.

In many ways, this is a very American crisis – one that would have never been 
possible without the revolving door between industry and government, and the 
overwhelming power of corporate money. The conditions that first made this 
situation possible have, if anything, gotten worse since OxyContin first hit 
the market. At least now we’re all paying attention.

— Jessica Loudis

Roland.
Toronto.

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