Hi Nickolas,

A good overview of the NGINX buffering mechanism can found on this 
third-party website 
<http://nginx.org/en/docs/http/ngx_http_proxy_module.html#proxy_max_temp_file_size>.
 
As described, “When buffering of responses from the proxied server is 
enabled, and the whole response does not fit into the buffers set by the 
proxy_buffer_size and proxy_buffers directives, a part of the response can 
be saved to a temporary file.”. Therefore, it will be important to look at 
the response generating these warning and check for any inconsistencies to 
determine if something is wrong with the App Engine Flexible environment. 
Also, determining if this warning is linked to any particular handler or 
endpoint may give additional insight to the root cause. Would you be able 
to provide some sort of stack trace of the response?

Now as to how to mitigate these warnings themselves, you may be able to 
disable the response buffer by setting the X-Accel-Buffering response 
header to “no” as demonstrated in this Request Handling concept page 
<https://cloud.google.com/appengine/docs/flexible/python/how-requests-are-handled#x-accel-buffering>
.

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