Hi Nichelle (and Brittany for tracking),

We've had a question arise on the gpc-dev call that is at the intersection of 
how we manage data for the PCORnet central office distributed research queries.

We've been operating on the understanding that for prep to research queries 
from PCORI, we will be hosting fully de-identified i2b2 and PCORnet CDM 
databases at each site.  The current model based on the data sharing is that 
prep to research queries of these resources will have Data Request Oversight 
but not IRB.

There's a discussion now of an added requirement that we also generate limited 
datasets with the precise dates.

-          This could either be a persistent database copy (what they'd prefer)

-          Or, could theoretically be a dataset for each project

The question is, when they want to distribute code that runs against these data 
files, is there a consistent interpretation of what IRB oversight is required?

What's the GPC IRB verdict?

-          Each research project has its own approved IRB protocol?

-          Or

-          There are exceptions approved by GPC IRB where if  data doesn't flow 
back with cell sizes less then 11, they don't need IRB

Is this a topic you've already addressed or should we bring this up at a 
meeting?

Russ Waitman, PhD
Director of Medical Informatics
Assistant Vice Chancellor for Enterprise Analytics
Associate Professor, Department of Internal Medicine
University of Kansas Medical Center, Kansas City, Kansas
913-945-7087 (office)
[email protected]<mailto:[email protected]>
http://www.kumc.edu/ea-mi/
http://informatics.kumc.edu<http://informatics.kumc.edu/>
http://informatics.gpcnetwork.org<http://informatics.gpcnetwork.org/> - a 
PCORnet collaborative

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