UTSW has Diagnosis and Procedures mapped to the GPC standard, they are just 
under a different project.  We also have the majority of the PCORI terminology 
useable in i2b2.  Due to different requirements of different project, ACT, GPC, 
PCORI, Local, it’s often necessary, or easier,  to deploy multiple versions of 
the same terminology.

I really think that SHRINE would give people a reason to map and use the shared 
terminologies, especially if it can save them time in reproducing queries.

Phillip

From: 
<[email protected]<mailto:[email protected]>> 
on behalf of Dan Connolly <[email protected]<mailto:[email protected]>>
Date: Monday, August 8, 2016 at 10:14 AM
To: "<[email protected]<mailto:[email protected]>>" 
<[email protected]<mailto:[email protected]>>
Subject: struggles with alignment on diagnoses, labs in PI-CONNECT federated 
query

I have aggregated data from 8 of 10 sites. Despite the fact that we agreed on 
our diagnosis ontology March 2014 
(#63<https://informatics.gpcnetwork.org/trac/Project/ticket/63>) and labs Nov 
2015 (#158<https://informatics.gpcnetwork.org/trac/Project/ticket/158>), terms 
were different enough that I had to scrape codes from various parts of paths 
and labels. We are not in a position to use SHRINE for queries with these terms.

UTSW is the only site whose IgG lab term path matches the GPC standard:
...

IgG Levels
In [54]:

igg_term = summary[summary.variable.str.contains(r'\bIgG\b|IMMUNOGLOBULIN G', 
case=False)].copy()

igg_path_72 = r'\GPC\Laboratory Tests\LP31388-9\LP15838-3\LP31769-0\LP14672-7\ 
'[4:-1]

igg_path_65 = r'\GPC\Laboratory 
Tests\LP31388-9\LP15838-3\LP31769-0\LP14672-7\LP43122-8\2465-3\ '[4:-1]

igg_term['aligned'] = igg_term.concept_path.apply(lambda p: 
p.endswith(igg_path_72) or p.endswith(igg_path_65))

per_site(igg_term)[['variable', 'concept_path', 'aligned']]

Out[54]:

        variable        concept_path    aligned
site



IU      0       0       0
KUMC    IgG (LP14672-7) \i2b2\Laboratory Tests\Chemistry\Protein\Immun...       
False
MCRF    2465-3: Igg     \i2b2\LP29693-6\LP29697-7\LP7834-7\55121-8\246...       
False
MCW     0       0       0
MU      IgG (LP14672-7) \i2b2\Laboratory Tests\Chemistry\Protein\Immun...       
False
UIOWA   IgG SerPl-mCnc  \i2b2\Labtests\LP31388-9\LP15838-3\LP31769-0\L...       
False
UNMC    IgG     \UNMC\Laboratory Results\Blood and body fluids...       False
UTHSCSA IgG SerPl-mCnc (2465-3) \i2b2\Laboratory 
Tests\Chemistry\Protein\Immun...       False
UTSW    IgG (LP14672-7) \i2b2\Laboratory Tests\LP31388-9\LP15838-3\LP3...       
True
WISC    IMMUNOGLOBULIN G        
\lab_information\lab_standard\igg\immunoglobul...       False


...

We're doing better on diagnoses, though 4 of 10 sites is still a minority:

...
Normalizing diagnosis codes
In [27]:

import re

​

def icd9_from_label(label):

    return [g1 for (g1, g2) in re.findall(r'(\d+(\.\d+)?)', label)]

​

icd9_from_label(u'283 Acquired hemolytic anemias')

Out[27]:

[u'283']

In [28]:

dx_term = summary[~ summary.variable.isin(igg_term.variable)].copy()

​

def find_icd9(x):

    name_code = icd9_from_label(x.variable)

    return ''.join(name_code if name_code

                   else x.concept_path.split('\\')[-2:])

​

dx_term['code'] = [find_icd9(row) for (ix, row) in dx_term.iterrows()]

In [29]:

pneumonia = dx_term[dx_term.code == '486'].copy()

gpc_486 = r'\i2b2\Diagnoses\ICD9\A18090800\A8359006\A8354357\A12966666\486\ 
'[20:-1]

pneumonia['aligned'] = pneumonia.concept_path.apply(lambda p: 
p.endswith(gpc_486))

per_site(pneumonia)[['variable', 'concept_path', 'code', 'aligned']]

Out[29]:

        variable        concept_path    code    aligned
site




IU      0       0       0       0
KUMC    486 Pneumonia, organism unspecified     
\i2b2\Diagnoses\ICD9\A18090800\A8359006\A83543...       486     True
MCRF    486 Pneumonia, organism unspecified     
\i2b2\Diagnoses\A18090800\A8359006\A8354357\A1...       486     True
MCW     0       0       0       0
MU      Pneumonia, organism unspecified (486)   \i2b2\Diagnoses\Diseases of the 
Respiratory Sy...       486     False
UIOWA   Pneumonia, organism unspecified \i2b2\Diagnoses\460-519\480-488\486\    
486     False
UNMC    486 Pneumonia, organism unspecified     
\i2b2\Diagnoses\A18090800\A8359006\A8354357\A1...       486     True
UTHSCSA 486 Pneumonia, organism unspecified     
\i2b2\Diagnoses\A18090800\A8359006\A8354357\A1...       486     True
UTSW    (486)Pneumonia, organism unspecified    
\i2b2\Diagnoses(ICD9CM)\DISEASES AND INJURIES\...       486     False
WISC    486: Pneumonia, organism unspecified    
\diagnosis_information\icd\icd09\001-999.99\46...       486     False

...


--
Dan


________________________________

UT Southwestern


Medical Center



The future of medicine, today.

_______________________________________________
Gpc-dev mailing list
[email protected]
http://listserv.kumc.edu/mailman/listinfo/gpc-dev

Reply via email to