> In this there is the following HTML code:

This isn't HTML, this looks like malformed javascript.

> app.manager.update =
> (
> ...
> manipulate function (strSymbol, objItem, objUpdate)
> ...
> strBgCol var = "#0000FF";
> ...
> )

Did you mean:

app.manager.update =
{
...
manipulate: function(strSymbol, objItem, objUpdate) {...},
...
strBgCol: "#0000FF",
...
}

> Manipulate function is called several times, and my need is to change the
> variable value strBgCol. Is it possible?

If strBgCol is a property of app.manager.update and not a local
variable in the manipulate function, yes:

unsafeWindow.app.manager.update.strBgCol = "#FF00FF"; //or whatever

But this is unsafe

http://wiki.greasespot.net/UnsafeWindow
http://wiki.greasespot.net/Category:Coding_Tips:Interacting_With_The_Page

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