http://blogs.timesofindia.indiatimes.com/ruminations/lifestyle-and-death-yoga-is-just-a-small-step-in-countering-big-auto-big-food-and-big-pharma/?utm_source=Popup&utm_medium=Old&utm_campaign=TOIHP

Lifestyle and death: Yoga is just a small step in countering Big Auto,
Big Food and Big Pharma
June 23, 2015, 12:05 AM IST Chidanand Rajghatta in Ruminations | Edit
Page, India | TOI

BOSTON: At a capacious convention centre in Boston, some 14,000
healthcare professionals — doctors, scientists, drug industry
executives — gathered for the 75th scientific sessions of the American
Diabetes Association earlier this month. Despite its professedly
‘American’ tag, hundreds of healthcare professionals from India and
China attended the meeting.

Here’s why: Give or take a few million, India (with 70 million
patients) and China (90 million) are the top two diabetes-stricken
countries in the world, followed by the US (30 million), whose free
market ways, including its food, transport and healthcare ethos, both
countries seek to copy.

As the meeting draws to a close on a balmy Monday, the centre is
boiling with excitement over the results of one of the biggest drug
trials for a diabetes medication called Januvia, belonging to the
sitagliptin class of drugs. Gliptins have been under a cloud for some
years now, suspected of causing heart failures, and Merck, the company
that owns sitagliptin, has subjected itself to a trial that other
gliptins from its rivals have failed.

If it is shown that sitagliptin-based Januvia does not cause heart
attacks, then Merck will be the biggest player standing in a field
where its Januvia is already the largest blockbuster in its portfolio,
with some 10 million subscriptions and $4 billion in annual sales
worldwide. India and China, with their burgeoning diabetes population,
will be particularly lucrative markets.
Which explains why Merck has flown in so many healthcare professionals
and journalists, present company included, from across the world. That
in itself, along with the fact that Merck has commissioned and paid
for the study by researchers at Oxford and Duke Universities, should
make it evident that the drug will get a thumbs-up.

But there have been instances of company-sponsored trials failing, so
executives from Merck and its India affiliate MSD say they are on pins
and needles, although they have readied a press release (declaring
victory!) as soon as results are announced.

When Januvia expectedly gets the all-clear, there is much bonhomous
backslapping, high-fives and hand-pumping between Merck execs,
researchers and physicians. The drug, introduced in 2006, is now good
for almost another decade and perhaps as much as $30 billion in
revenues over the next decade, even as its rivals have fallen by the
way side. More importantly, gliptins as a class of drugs cannot all be
condemned as heart-attack causers, although numerous other lesser side
effects are quietly glossed over, buried in fine print and fast talk.

Such scenes are repeated at many healthcare conventions across the
world, which are but fora for legitimising drug use. The culture of
understating side effects and propounding medication as the first line
of defence (and offence), to treat what Mumbai’s cardio-metabolic guru
Dr Hemant Thacker calls ‘a lifestyle, not a disease’, is what should
exercise our minds hours after the World Yoga Day.

Drug companies jealously guard their turf, their patents and their
profits, and they have no stake in keeping us healthy. Doctors, for
the most part, are trained to dispense medication, not talk you into
lifestyle changes that most people are not disciplined enough to make.
The result: Blockbuster drugs from the family of statins (which treat
high cholesterol, vilified as a heart disease provocateur) and
gliptins (for diabetes), both prescribed enthusiastically by
physicians, generate more than a trillion dollars in revenues for Big
Pharma. The drug companies in turn plow in big money into the
political system (particularly in the US) to get protection and
profits.

The other elephants in the room: Big Food and Big Auto, which have
combined to subvert an active lifestyle based on traditional coarse
grains and rough activity, and turned us into sedentary couch potatoes
feasting on mass-produced, industrial grade carbs and refined foods.

This includes an overdose of sugar in a society that calls for sweets
on every happy occasion. Sweet are the uses of adversity, fluted the
Bard, but it turns out that sweet is the new adversary. Sugar, says Dr
Shashank Joshi, one of several leading endocrinologists from India who
was at Boston, is the new tobacco. Indeed, in many parts of India,
diabetes is colloquially called the sugar disease.

India is particularly vulnerable to this assault. It appears we may
also be genetically predisposed to these ailments because of a dodgy
gene (dubbed the ‘thrifty gene’) that causes us to hoard calories.
Perhaps, joked one endocrinologist, who calls it the ‘fuel storage
gene’, in anticipation of another famine. But for the most part, we
have only ourselves to blame — for succumbing to the blandishments of
Big Food and Big Auto, underwritten by promises from Big Pharma of
managing our lifestyle excesses.

***Indeed, recent studies show that India is undergoing an
‘epidemiological transition’ consistent with lifestyle changes. More
people in India now die of non-communicable lifestyle ailments (like
diabetes, heart attack, cirrhosis) than communicable diseases (like
tuberculosis, measles, flu) that snuffed out lives in the last
century. This is largely avoidable, if not downright preventable, with
a public policy that encourages lifestyle changes. Yoga, or any other
form of workout sans political motives and religious underpinnings, is
but a small first step. Many more twists and turns are needed to avoid
the clutches of the Big Three.*** [Emphasis added.]

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Peace Is Doable

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