On 10/31/18 8:36 AM, Ramon Guixà wrote:
Hi again,

Just confirmed that when I run the same tpr file for 500 ns using only
CPUs, no problems arise, please check it out here:
https://drive.google.com/open?id=1aI2wr2GvNjCfj4c4J0pmgCzV0ak5FRE6

<https://drive.google.com/open?id=1aI2wr2GvNjCfj4c4J0pmgCzV0ak5FRE6>
I mean, is this a bug? Most of my computer resources are GPU-based, is
there anything I can change in the set-up or compilation so I can simulate
using gromacs, CHARMM36, and GPUs?

Do you have access to a GPU with ECC? I wonder if this is a software bug or something going wrong with the GPU, like a bit flip. I've experienced this very rarely with consumer-grade cards like GTX 980, certainly not with the regularity you're seeing, though. There's clearly something wrong in your system to trigger such a sudden change. I pulled all the energy terms from your .edr file but it's hard to determine cause/effect in any of them.

-Justin

--
==================================================

Justin A. Lemkul, Ph.D.
Assistant Professor
Virginia Tech Department of Biochemistry

303 Engel Hall
340 West Campus Dr.
Blacksburg, VA 24061

[email protected] | (540) 231-3129
http://www.thelemkullab.com

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