USB as a transport isn't currently supported. There was a recent discussion 
around this with further details 



On Tuesday, February 13, 2018 at 9:44:49 AM UTC-8, 
> Hey,
> is it possible to somehow use gRPC with USB, be it with 3rd party 
> implementations? The bandwith limitation of Gigabit Ethernet is an issue 
> for us and we'd like to achieve the data rates of a USB connection for big 
> data types.

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