[H] vista 64 and games

[Winterlight]

I finally got around to attempting to install a game in Vista 64 SP1. 
I bought Gears of War for Windows and when I put the DVD in it 
doesn't even appear in explorer let alone install.

Then I tried my Quake 4 DVD and while that appears in explorer I am 
immediately informed that it isn't supported.

So what does work? Or maybe it has something to do with my dual Asus 
4870s set to Crossfire??