Dear HCP-Freesurfers,

I'd like to extract the mean cortical thickness of a ROI I generated for
subjects from the human connectome project (HCP). The ROI is a mask in
nifti format and its dimensions correspond to the
HCP_subject/MNINonLinear/T1w_restore_brain.nii.gz file. I'd like to use the
normalized, structural HCP data from the preprocessed Freesurfer pipeline.
Trying to follow the instruction on the Freesurfer Wiki (
http://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness), I
encountered several problems. I hope you can help me!

How do I map the subject thickness data to the fsaverage subject? There are
several "thickness" files in the HCP dataset - which one should be used? I
created a "surf" folder and filled it with the supposedly relevant files.
Is the used file for the --surfreg flag correct (see command line below)?
 I tried to use the following command:

 mri_surf2surf --srcsubject 100408 --srcsurfval
100408.R.thickness.32k_fs_LR.shape.gii --trgsubject fsaverage --trgsurfval
rh.checkthickness.fsaverage.mgh --hemi rh --surfreg
100408.R.sphere.reg.native.surf.gii

This error message resulted:

Source registration surface changed to 100408.R.sphere.reg.native.surf.gii
Target registration surface changed to 100408.R.sphere.reg.native.surf.gii
srcsubject = 100408
srcval     = 100408.R.thickness.32k_fs_LR.shape.gii
srctype    =
trgsubject = fsaverage
trgval     = rh.checkthickness.fsaverage.mgh
trgtype    =
srcsurfreg = 100408.R.sphere.reg.native.surf.gii
trgsurfreg = 100408.R.sphere.reg.native.surf.gii
srchemi    = rh
trghemi    = rh
frame      = 0
fwhm-in    = 0
fwhm-out   = 0
label-src  = (null)
label-trg  = (null)
OKToRevFaceOrder  = 1
Reading source surface reg
/usr/local/freesurfer/subjects/100408/surf/rh.100408.R.sphere.reg.native.surf.gii
Loading source data
** failed to open GIFTI XML file
'/usr/local/freesurfer/subjects/100408/surf/100408.R.thickness.32k_fs_LR.shape.gii'
MRISreadGiftiAsMRI: gifti_read_image() returned NULL
ERROR: could not read 100408.R.thickness.32k_fs_LR.shape.gii as type 27


I appreciate your help.

Cheers,
Jessica

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