Hi Yan,

I can speak for the preprocessed DTI data that it is the data with all of the 
preprocessing pipelines described in (Glasser et al. 2013).

Depending on what you want to analyze, it could be in your benefit to start at 
the preprocessed data. For DTI, they have already corrected the distortions as 
well as the eddy currents so the data has had it's motion correction completed 
already.

With the preprocessed data you could immediately put the data in FSL and start 
at DTIFIT, TBSS or otherwise. However, as described in the paper, BedpostX has 
not been run on the data.

Cheers,

_______________________________________
Bryan Chiu
Undergraduate Research Assistant
Aging, Mobility, and Cognitive Neuroscience Lab
Djavad Mowafaghian Centre for Brain Health
Department of Physical Therapy
Faculty of Medicine
University of British Columbia

Date: Wed, 1 Oct 2014 10:24:24 -0500
From: "Jennifer Elam" <[email protected]>
Subject: Re: [HCP-Users] [HCP-Info] [Contact Form]: about data
To: '??' <[email protected]>
Cc: [email protected], [email protected],
        [email protected]
Message-ID: <[email protected]>
Content-Type: text/plain; charset="gb2312"

In the HCP diffusion acquisition protocol, we collect six diffusion series
(each set of directions in LR and RL phase encoding directions), and that is
reflected in the unprocessed data. The HCP diffusion preprocessing pipeline
starts by intensity normalizing the mean b0 image across the six diffusion
series. These phase encoding direction reversed b0 pairs are used to
estimate the EPI distortion using the ?topup? tool ( Andersson et al.,
2003) in FSL5.



In the preprocessed fMRI series data, each rfMRI scan was collected with
each of the two phase encoding directions. The preprocessing is done
?within run? rather than across runs, so that is why you see data for the
4 scans: (REST1, REST2, for LR and RL).



The single band reference scan (SBRef) serves as the reference for motion
correction, EPI distortion correction and for more accurate EPI to T1w
registration.



I would recommend you look at Glasser
<http://www.sciencedirect.com/science/article/pii/S1053811913005053> et al.
2013 for more information on the diffusion and functional preprocessing.



Best,

Jenn



Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
[email protected]
www.humanconnectome.org<http://www.humanconnectome.org>



From: ?? [mailto:[email protected]]
Sent: Tuesday, September 30, 2014 4:31 PM
To: Jennifer Elam
Cc: [email protected]; [email protected];
[email protected]
Subject: Re: Re: [HCP-Users] [HCP-Info] [Contact Form]: about data




But I still feel confused. You means I can use any group data to get the
brain fiber such as  L-R and 95 directions? But why are there only one data
in processed data?

In addition, I found in fMRI data, you keep the L-R and R-L data in both
unprocessed data and processed data. So if I deal with fMRI, can I analyze
any group data. What different can I get?

 Last, I find a lot of  *_SBRef.nii in the unprocessed data. I don't know
what this data describe?







-----????-----

???: "Jennifer Elam" <[email protected]>
????: 2014?10?1? ???
???: [email protected]
??: [email protected], [email protected]
??: Re: [HCP-Users] [HCP-Info] [Contact Form]: about data

Hi Yan,



We provide our diffusion data in separate unprocessed and minimally
preprocessed data packages so that users need only download one or the
other, depending on whether they want to process data from the beginning or
proceed with analysis steps after normal preprocessing steps have been
applied.



Others on the HCP-users list may be able to help you with your other
questions.



Please sign up for the HCP-users email list
<http://humanconnectome.org/contact/#subscribe>  and ask your questions in
that forum so that all can benefit from the responses.



Best,

Jenn



Jennifer Elam, Ph.D.

Outreach Coordinator, Human Connectome Project

Washington University School of Medicine

Department of Anatomy and Neurobiology, Box 8108

660 South Euclid Avenue

St. Louis, MO 63110

314-362-9387

[email protected]

www.humanconnectome.org<http://www.humanconnectome.org>





-----Original Message-----
From: [email protected] 
[<https://www.mail.ubc.ca/owa/UrlBlockedError.aspx>mailto:info-bounces@humanconnectome.
org] On Behalf Of [email protected]
Sent: Saturday, September 27, 2014 10:19 AM
To: [email protected]
Subject: [HCP-Info] [Contact Form]: about data



Name: yan tang



Email:  <mailto:[email protected]> [email protected]



Institution: TTU



Subject: [Contact Form]: about data



Comments:

I am beginner. I want to download the DTI data but are conflused by the
processed data and unprocessed data.

1)The unprocessed data contains the NIFTI-formatted pairs (L-R, R-L) of
diffusion scans for all directions (95,96,and 97). And processed data only
include diffusion weighting (bvals), direction (bvecs), time series, brain
mask, and a file (grad_dev.nii.gz). Why? what did you only keep?

2)In the processed data, whether the file of *_SBRef.nii describe the B0?

3)I download the processed data, but I couldn't use the Micron to open the
data.nii. Why? I download two subjects. Both subjects couldn't be opened


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