Hi Mahsa,
I think you are going to have to be more specific for anyone to be able to help you.  What is your goal?  And  what tools are you using and how are you trying to apply the masking.   For example, if you are trying to work with the resting state volume data in Matlab/SPM, you may find that the file sizes are too large to work conveniently in Matlab.  

cheers,
-MH

-- 
Michael Harms, Ph.D.
-----------------------------------------------------------
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. Tel: 314-747-6173
St. Louis, MO  63110 Email: [email protected]

From: Mahsa Alizade shalchy <[email protected]>
Reply-To: Mahsa Alizade shalchy <[email protected]>
Date: Tuesday, October 14, 2014 2:23 PM
To: Hcp-users <[email protected]>
Subject: [HCP-Users] ROI extraction of rest fmri data

Dear all
Hi

I'm working on the rest fmri data(fix extended) and I have a problem regarding masking. Since the data is very large (4D image with 1200 volumes), I could not apply masking.Could you please help me on this matter?
Many thanks in advance.
Ps:I have 8 G of RAM available.

Best,
mahsa

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