1. I would probably try to upsample rather than downsample to take advantage of your 0.9mm T1w (we’ve not tried 0.9mm before, but given how much better 0.8mm is than 1mm, it would probably be worth it).  You could see if things run smoothly if you just use the 0.8mm template, or otherwise could create 0.9mm versions by downsampling one of the higher resolutions.  
  2. Just take the value in seconds directly from DICOM field (0019,1018).  Which in your case would be 0.0000098 and 0.0000026.
Peace,

Matt.

From: Matthew George Liptrot <[email protected]>
Date: Tuesday, November 25, 2014 at 9:40 AM
To: "[email protected]" <[email protected]>
Subject: [HCP-Users] PreFreeSurferPipeline

Hi,

I’ve been adapting the extremely useful HCP pipelines for application to our own data, and would like some advice regarding the PreFreeSurferPipeline.
  1. The HCP T1w and T2w data are at 0.7mm resolution, whereas our T1w is 0.9mm, and T2w is 1.0mm (both isotropic). Would it be best to register both to the 1mm MNI template?
  2. For the Readout Distortion Correction, using Siemens Gradient Echo Field Maps (Siemens Verio 3T), I need to specify the “T1wSampleSpacing” and “T2wSampleSpacing”, which I presume is the dwell-time. In the example script (PreFreeSurferPipelineBatch.sh), values of 7.4 (T1) and 2.1 (T2) microsecs are pre-coded, and reference DICOM field (0019,1018). In our images, this field contains the values 9800 (T1) and 2600 (T2), which would imply that they are specified in nanoseconds. Also, if I use the formula DwellTime = 1 / (PixelBandwidth * NumberPhaseEncodeSteps), then I get 19.7 (T1) and 5.6 (T2) microseconds. I get PixelBandwidth from DICOM (0018,0095), and NumberPhaseEncodeSteps from DICOM (0018,0089). Which is correct? Why aren’t they the same (GRAPPA correction, maybe?)
Many thanks in advance for any pointers

Cheers,

M@
-- 
Matthew George Liptrot

Department of Computer Science
University of Copenhagen
Section for Cognitive Systems
Department of Applied Mathematics and Computer Science
Technical University of Denmark


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