How much RAM do you have?  The CIFTI files use far less RAM than the
volume files, but contain all the grey matter information represented in a
way that makes combining across subjects more accurate.  If you don¹t use
all the data your estimates of the subject¹s functional connectivity will
be noisier and generally less stable (one 15 min run looks more different
than another than if you compared two sets of 1 hour¹s worth of data).
Also there are some left/right asymmetries in the data induced by the
LR/RL phase encoding directions, which some people perceive as a problem
(though if we had used AP/PA there would still be asymmetries
posterior/anterior).

Peace,

Matt.

On 1/23/15, 6:44 AM, "Chao Liu" <[email protected]> wrote:

>Dear HCP Experts,
>
>I am inspecting the HCP rfMRI data. For each subject, there are two
>sessions with 2 runs (LR&RL) in each session, yielding 4 files in total.
>Although we can concatenate all the four time series and do the
>correlation, I found the memory needed is more than the memory I have on
>lab computer, leading to a very slow calculation. So I am wondering the
>difference between using only one run and using all the four runs. Will
>it give wrong results if I use only one run?
>
>Many thanks!
>Chao


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