This may or may not be helpful, but, I was and still am fascinated by 
grayordinates.

Alpay,

I think you are asking for a mapping from grayordinates to a standard volume 
representation of the functional areas, such as MNI or Talairach coordinates. I 
think Matt might be resistant because the modeling of the pancake of the 
neocortex as a grid of voxels may not be conceptually clean.

It seems that if there were an ideal folding of the neocortex into a volume, 
then you would have your mapping.

So, I have two questions:

Is there an ideal folding of the neocortex into a volume?

Is there a geometric path for the grayordinates? Does anyone have a graph? If I 
ever come up with one, does anyone else want to see it?

I’m an armchair neuroscientist and I got sent to Resting State 2014 as sort of 
a reward for debugging a deep mystery with our aging volume rendering hardware 
on a newer server. I’ve been in 3D graphics forever and medical imaging for 17 
years. I am a coordinate system geek. I tried to see if there was a any sort of 
geometric path for the grayordinates. 
http://www.jch.com/jch/notes/RestingState2014/grayordinates.html but then I had 
to get back to my day job.

YON - Jan C. Hardenbergh <> jch.com <> Pixelsmith
Deadlines may impose an artificial thought process, but, 
without them there would be no thought process at all.

> On Mar 31, 2015, at 2:11 PM, Alpay Özcan <[email protected]> wrote:
> 
> Matt,
> thank you very much for your explanations.
> 
> Taking a pragmatic view, I just loaded the time series data from the 
> grayordinates file
> rfMRI_REST1_LR_Atlas_hp2000_clean.dtseries.nii
> 
> picked up one of the time series and subtracted it from
> all of the time series in the file
> rfMRI_REST1_LR_hp2000_clean.nii.gz
> 
> There was no match.
> 
> This answers my question about the location
> of the grayordinates in the full MNI space time series data.
> 
> Basically, the time series in grayordinates from the file
> rfMRI_REST1_LR_Atlas_hp2000_clean.dtseries.nii
> 
> are not a subset of MNI space 91x109x91 1200 time point time series data 
> from the file
> rfMRI_REST1_LR_hp2000_clean.nii.gz
> 
> Therefore, grayordinate time series data are obtained after registration 
> transformations targeting the surface points, I am guessing, as you 
> explained in your e-mails.
> 
> Please allow me to follow up by asking if there is a segmentation or
> a binary mask on the 91x109x91 data set (rfMRI_REST1_LR_hp2000_clean.nii.gz)
> 
> for example using the 1st time point brain volume
> that gives the segmentation for the cortex?
> 
> Thanks in advance and thank you for your patience,
> alpay
> 
> 
> On 28-Mar-15 11:19, Glasser, Matthew wrote:
>> The surface grayordinates simply don’t exist in a 3D cartesian space, they
>> exist on a 2D surface mesh made up of triangular tiles and their neighbors
>> are determined by the topology of that mesh.  Most vertices have six
>> neighbors, but a very few have 5 (also those along the medial wall may
>> have fewer valid neighbors for a different reason).  You find the
>> neighbors of surface grayordinates by looking at the topology section of a
>> GIFTI surface file.  The first data array of a GIFTI surface file are the
>> 3D coordinates of each vertex, the second data array are the topological
>> relationships between the vertices that form each triangular tile.
>> Individual subject standard mesh surfaces may have different 3D
>> coordinates across subjects, but always have the same topology and hence
>> are said to be on the same mesh.  It is this standard mesh that is the
>> equivalent of a standard voxel grid in volume space.  We provide the
>> command wb_command -surface-geodesic-rois that you can use to find the
>> nearest surface vertices within some number of mm of a given vertex.
>> There is the command wb_command -surface-geodesic-distance which you can
>> use to compute the distances between a vertex and the rest of the surface
>> (you can limit this to a max distance to speed it up).  Finally, there is
>> the command wb_command -cifti-export-dense-mapping that will tell you
>> which grayordinate indices correspond to which surface vertex indices or
>> subcortical voxels.  Perhaps one or more of these will address your
>> request.
>> 
>> If for some reason you need to know about an individual subject’s voxels,
>> you can work with the data before it has been resampled to grayordinates
>> space and then resample any results to grayordinates space after you’re
>> done (however you’ll want to be sure you are only working with voxels
>> inside the greymatter ribbon).  You’ll also need to be careful you don’t
>> accidentally average across subjects in volume space or smooth the data in
>> volume space.  At some point we’ll make it possible to completely reverse
>> the grayordinates projection (e.g. go from group average results in
>> grayordiantes space to individual subject native or MNI volume space), but
>> this has not yet been a high enough priority for our developers, as most
>> people don’t need to run their analysis in that direction.
>> 
>> I’ll be honest that despite your lengthy e-mail, I’m not really clear what
>> you are doing and hence why you need what you are requesting.  If you
>> don’t want to post sensitive details in public, you can e-mail me off the
>> list.  If you don’t want to tell me specifically what you’re up to, I’m
>> more limited in my ability to help.
>> 
>> Peace,
>> 
>> Matt.
>> 
>> On 3/28/15, 8:44 AM, "Alpay Özcan" <[email protected]> wrote:
> _______________________________________________
> HCP-Users mailing list
> [email protected]
> http://lists.humanconnectome.org/mailman/listinfo/hcp-users







_______________________________________________
HCP-Users mailing list
[email protected]
http://lists.humanconnectome.org/mailman/listinfo/hcp-users

Reply via email to