Inline replies.

On Wed, Nov 18, 2015 at 8:47 AM, Matthew George Liptrot <
[email protected]> wrote:

> Hi,
>
> Thanks both of you.
>
> On 17/11/15 21:32 , "Timothy Coalson" <[email protected]> wrote:
>
> So, cifti is not a 1:1 mapping to surface vertices.  If what you plan to
> use can read gifti, the less error-prone route is probably to use
> -cifti-separate to get a nifti volume and gifti files that do have a 1:1
> mapping to vertices.
>
>
> @Tim: By “not a 1:1 mapping to surface vertices”, do you mean:
>
>    1. The CIFTI data-value:vertex mapping is not necessarily bijective
>    (unique)?
>    2. The CIFTI data-value:vertex mapping is not necessarily complete
>    (some vertices may not be represented)?
>    3. A combination of 1 & 2?
>
> I hope it’s (2), because otherwise I’m confused (again!).
>

Just (2), yes.  Technically this also means it is not bijective, but the
mapping of cifti index to vertex/voxel is injective (no two cifti indices
represent the same vertex or voxel).


> A follow-on question is then why would it be less error-prone to use
> -cifti–separate (as opposed to e.g. -cifti-export-dense-mapping)?
> I can see that using -cifti-export-dense-mapping on the Conn3.dconn.nii
> file lists a non-contiguous mapping of node-IDs:Vertex-Ids, presumably due
> to the omission of the vertices on medial wall that are covered by the
> subcortical ROIs, i.e.
>

I called it less error-prone because it applies the cifti->vertex/voxel
mapping for you, rather than making you figure out how to do it.


> CortexLeft, Total entries: 29696 (Node IDs:  0-29695,  Vertice IDs:
> 0-32491)
> CortexRight, Total entries: 29716 (Node IDs: 29696-59411, Vertice IDs:
> 0-32491)
> SubCortical, Total entries: 31870 (Node IDs: 59412-91281)
>
> Is this what you were referring to?
>

Yes.


> I then tried using some of your suggestions to extract the labels from the
> aparc32k atlas in 100307/MNINonLinear/fsaverage_LR32k.
> I tried the following 3 workflows:
>
> (A)
> > wb_command -cifti-separate 100307.aparc.32k_fs_LR.dlabel.nii COLUMN
> -label CORTEX_LEFT aparc32k_fs_LR_dlabel_Separated_CortexLeft.gii
> > wb_command -gifti-convert ASCII
> aparc32k_fs_LR_dlabel_Separated_CortexLeft.gii
> aparc32k_fs_LR_dlabel_Separated_GiftiConvert_CortexLeft.txt
> > cp aparc32k_fs_LR_dlabel_Separated_GiftiConvert_CortexLeft.txt
> aparc32k_fs_LR_dlabel_Separated_GiftiConvert_CortexLeft_LabelsOnly.txt
> # Strip away all header/footer XML codes from
> aparc32k_fs_LR_dlabel_Separated_GiftiConvert_CortexLeft_LabelsOnly.txt
> using emacs
> > wc -l
> aparc32k_fs_LR_dlabel_Separated_GiftiConvert_CortexLeft_LabelsOnly.txt
> 32492
>
> (B)
> > wb_command -gifti-convert ASCII 100307.L.aparc.32k_fs_LR.label.gii
> L_aparc32k_fs_LR_label_GiftiConvert_CortexLeft.txt
> > cp L_aparc32k_fs_LR_label_GiftiConvert_CortexLeft.txt
> L_aparc32k_fs_LR_label_GiftiConvert_CortexLeft_LabelsOnly.txt
> # Strip away all header/footer XML codes from
> L_aparc32k_fs_LR_label_GiftiConvert_CortexLeft_LabelsOnly.txt using emacs
> > wc -l L_aparc32k_fs_LR_label_GiftiConvert_CortexLeft_LabelsOnly.txt
> 32492
>
> (C)
> > wb_command -cifti-convert -to-text 100307.aparc.32k_fs_LR.dlabel.nii
> aparc32k_fs_LR_dlabel_ConvertedToText_NodeID_LabelOnly_CortexAll.txt
> > wc -l
> aparc32k_fs_LR_dlabel_ConvertedToText_NodeID_LabelOnly_CortexAll.txt
> 59412
>
> As you can see, they all gave the expected number of outputs (the latter
> one with the medial wall vertices already removed)
>

(C) is obviously not going to match index for index, and the formatting of
the below list got messed up, but...


> However, when I look at the first few labels, there are some differences
> between set (A) and (B):
>  A     B      C
> 10 10 10
> 29 29 29
> 24 24 24
> 28 28 28
> 11 11 11
> 31 31 31
> 27 27 27
> 0 -1
>

I don't know why -1 is here, that is very unusual for a gifti label file.
It looks like it is used as the unlabeled key, unlike the cifti version
that uses 0 - try -cifti-label-export-table and -label-export-table on the
two files and see if something shows up for -1, like the "???" key.

13
> 13 13 15
> 15 15 35
> 35 35 35
> 35 35 10
> 10 10 10
> 10 10 10
> 10 10 10
> 10 10 10
> 10 10 10
> 10 10 10
> 10 10 10
> 10 10 10
> 10 10 10
> 0 10 10
> 0 10 10
> 0 10 10
> 0 10 10
> 0 10 10
> 0 10 10
> 0 -1 10
> 0 -1 10
> 0 -1 10
> 0 -1 10
> 0 -1 10
> 0 -1 10
> 0 -1 10
> 0 -1 10
>
> Shouldn’t these two give the same? Or maybe this is the errors you were
> referring to?
>
> Thanks in advance,
>
> M@
>
>
> Otherwise, have a look at -cifti-label-export-table, -cifti-convert
> -to-text (other options exist here for nifti-1 and gifti), and
> -cifti-export-dense-mapping in order to get text files that can get you to
> the vertex mapping.
>
> Tim
>
>
> On Tue, Nov 17, 2015 at 11:25 AM, <[email protected]> wrote:
>
>> Try this:
>>
>> wb_command -gifti-convert ASCII my.label.gii ascii.label.gii
>>
>> If needed, strip everything up to <Data>, and then the label values are
>> listed in vertex sequence.
>>
>> Will need to think about the HOA question.  Hmmm.
>>
>> Donna
>>
>> > Hi Donna,
>> >
>> > Many thanks for your thorough reply. I can see that I wasn’t very
>> clear
>> > on explaining what we are trying to achieve – I’ll try to clarify
>> > things a little :-)
>> >
>> > What we have done so far:
>> > Generated Conn3.dconn.nii files: 92K x 92K structural connectivity
>> > matrices from the DWI data in FSL’s matrix3 format (WM seeds, cortical
>> > surface & subcortical voxels as targets).
>> > This provides us with connectivity matrices whose nodes are (to the
>> limit
>> > of the HCP registration pipeline) anatomically matched across subjects.
>> >
>> > What we are analyzing:
>> > Machine-learning parcellation of these connectivity matrices.
>> >
>> > What we would like to do:
>> > Compare our machine-learning parcellations with previously published /
>> > commonly-used ones.
>> > For this we would like to be able to obtain, for each atlas, a label per
>> > node of the connectivity matrices.
>> > For some atlases, e.g. Desikan-Killiany, I realise that these
>> labels:node
>> > mappings will vary per subject as the atlas is adapted according to the
>> > individual’s gyrification patterns.
>> > For other atlases though, e.g. the Gordon 2014 atlas, the label:node
>> > mapping is fixed.
>> > It would also be great if we could compare against some MNI-based
>> > parcellation schemes, such as the Harvard-Oxford. (Other suggestions
>> > welcome!)
>> >
>> > So to my questions! :-)
>> >
>> > 1) What is the best way to get the per-subject label:node mapping from
>> the
>> > existing *.dlabel.nii and *.label.gii files?
>> > I was thinking of using something like:
>> >
>> > wb_command -file–information
>> >
>> 100307/MNINonLinear/fsaverage_LR32k/100307.aparc.a2009s.32k_fs_LR.dlabel.nii
>> >
>> > which gives me (with a bit of filtering) a parcel:label mapping.
>> > Then using:
>> >
>> > wb_command -nifti-information -print-matrix
>> >
>> 100307/MNINonLinear/fsaverage_LR32k/100307.aparc.a2009s.32k_fs_LR.dlabel.nii
>> >
>> > to give me a vertex:parcel mapping. Then I need to stitch the two
>> together
>> > somehow.
>> > Are these steps correct? Is there a better (easier) way?
>> >
>> > 2) Would I use the same method for the Gordon atlas (which I understand
>> is
>> > provided on the standard 32K mesh)?
>> >
>> > 3) How would I do this for, e.g. the Harvard-Oxford atlas? Should I map
>> > the voxelwise parcels onto the 32K mesh first and then use the same
>> method
>> > as for (2)?
>> >
>> > I’m still a surface-space novice, but I hope this is a bit clearer now
>> > :-)
>> >
>> > Many thanks for any help/advice!
>> >
>> > Cheers,
>> >
>> > M@
>> >
>> > On 13/11/15 20:25 , "Donna Dierker"
>> > <[email protected]<mailto:[email protected]>> wrote:
>> >
>> > Hi Matthew,
>> >
>> > The aparc files Jenn meant are generated by Freesurfer, but we make them
>> > available in cifti (*dlabel.nii) and gifti (*.label.gii) formats:
>> >
>> > * 164k standard mesh
>> > Structural_preproc/MNINonLinear/994273.aparc.164k_fs_LR.dlabel.nii
>> >
>> Structural_preproc/MNINonLinear/994273.aparc.a2009s.164k_fs_LR.dlabel.nii
>> > Structural_preproc/MNINonLinear/994273.L.aparc.164k_fs_LR.label.gii
>> >
>> Structural_preproc/MNINonLinear/994273.L.aparc.a2009s.164k_fs_LR.label.gii
>> > Structural_preproc/MNINonLinear/994273.R.aparc.164k_fs_LR.label.gii
>> >
>> Structural_preproc/MNINonLinear/994273.R.aparc.a2009s.164k_fs_LR.label.gii
>> > * 32k standard mesh
>> >
>> Structural_preproc/MNINonLinear/fsaverage_LR32k/994273.aparc.32k_fs_LR.dlabel.nii
>> >
>> Structural_preproc/MNINonLinear/fsaverage_LR32k/994273.aparc.a2009s.32k_fs_LR.dlabel.nii
>> >
>> Structural_preproc/MNINonLinear/fsaverage_LR32k/994273.L.aparc.32k_fs_LR.label.gii
>> >
>> Structural_preproc/MNINonLinear/fsaverage_LR32k/994273.L.aparc.a2009s.32k_fs_LR.label.gii
>> >
>> Structural_preproc/MNINonLinear/fsaverage_LR32k/994273.R.aparc.32k_fs_LR.label.gii
>> >
>> Structural_preproc/MNINonLinear/fsaverage_LR32k/994273.R.aparc.a2009s.32k_fs_LR.label.gii
>> > * native mesh
>> >
>> Structural_preproc/MNINonLinear/Native/994273.aparc.a2009s.native.dlabel.nii
>> > Structural_preproc/MNINonLinear/Native/994273.aparc.native.dlabel.nii
>> >
>> Structural_preproc/MNINonLinear/Native/994273.L.aparc.a2009s.native.label.gii
>> > Structural_preproc/MNINonLinear/Native/994273.L.aparc.native.label.gii
>> >
>> Structural_preproc/MNINonLinear/Native/994273.R.aparc.a2009s.native.label.gii
>> > Structural_preproc/MNINonLinear/Native/994273.R.aparc.native.label.gii
>> >
>> > If you get the structural extended packages, you can get the original
>> > Freesurfer subject directory (e.g. Structural_preproc/T1w/994273).
>> >
>> > Note these include not only the Desikan-Killiany (aparc), but also the
>> > Destrieux (aparc.a2009s):
>> >
>> > https://surfer.nmr.mgh.harvard.edu/fswiki/CorticalParcellation
>> >
>> > The only relation these have to the Conte69 is that they are both
>> > available in the 164k and 32k standard meshes.  These are very nice
>> > parcellations Freesurfer provides in normal processing; we just make
>> them
>> > available on different meshes/formats for the HCP subjects.
>> >
>> > I assume you are interested in anatomical parcellations only, and not
>> > functional (e.g.,
>> > https://surfer.nmr.mgh.harvard.edu/fswiki/CorticalParcellation_Yeo2011
>> ).
>> > I think you will see improved parcellations coming out soon, so stay
>> > tuned.
>> >
>> > I am not a diffusion expert, so I don't have a good feel for what you
>> are
>> > trying to do, though it may involve identifying where tracts terminate
>> and
>> > seeing how often varying parcellations agree using the same tracts
>> (???).
>> >
>> > Donna
>> >
>> >
>> > On Nov 13, 2015, at 8:35 AM, Matthew George Liptrot
>> > <[email protected]<mailto:[email protected]>> wrote:
>> >
>> > Hiya,
>> > We would like to compare several parcellation schemes with the results
>> of
>> > structural connectivity on the HCP data (we have generated dense
>> > connectome data for several subjects).
>> > The Freesurfer parcellation (which is based upon the Conte69 atlas?) is
>> > already provided on the 32K subject mesh, but we would like to compare
>> > others, e.g. Desikan-Killiany, Harvard-Oxford, microstructure etc. In
>> > short:
>> > 1) What would be the optimal way to do this?
>> > 2) Which wb_commands should we use?
>> > 3) Which atlases would people recommend (we want to look at replication
>> > performance across subjects)
>> > 4) There seems to only be a small subset of Brodmann areas in the
>> > distributed subjects’ 32K CIFTI files (mainly the visual cortex and
>> > areas around pre- and post-central gyrus). Any reason why the rest are
>> > missing?
>> > Thanks in advance for any pointers!
>> > Cheers,
>> > M@
>> > On 4/11/15 23:17 , "Jennifer Elam"
>> > <[email protected]<mailto:[email protected]>> wrote:
>> > Hi Vishal,
>> > Also, the FreeSurfer-generated aparc and aparc.a2009s non-overlapping
>> > parcellations for each subject are available on the 32k_fs_LR mesh and
>> > 164k mesh in the Structural preprocessed package for each subject. These
>> > are available as GIFTI label files per hemisphere and as CIFTI dlabel
>> > files (both hemispheres).
>> >
>> > Best,
>> > Jenn
>> >
>> > Jennifer Elam, Ph.D.
>> > Outreach Coordinator, Human Connectome Project
>> > Washington University School of Medicine
>> > Department of Anatomy and Neurobiology, Box 8108
>> > 660 South Euclid Avenue
>> > St. Louis, MO 63110
>> > 314-362-9387
>> > [email protected]<mailto:[email protected]>
>> > www.humanconnectome.org
>> >
>> > From:
>> > [email protected]<mailto:
>> [email protected]>
>> > [mailto:[email protected]] On Behalf Of Harms,
>> > Michael
>> > Sent: Wednesday, November 04, 2015 3:40 PM
>> > To: Vishal Patel;
>> > [email protected]<mailto:[email protected]>
>> > Subject: Re: [HCP-Users] Hcp Data with non-overlapping parcellations
>> >
>> >
>> > Hi Vishal,
>> > There is a version of the hard parcellation from Gordon et al. (Cerebral
>> > Cortex, 2014) available as a CIFTI 'dlabel.nii' file, if you are
>> > interested in that.
>> >
>> > cheers,
>> > -MH
>> >
>> > --
>> > Michael Harms, Ph.D.
>> > -----------------------------------------------------------
>> > Conte Center for the Neuroscience of Mental Disorders
>> > Washington University School of Medicine
>> > Department of Psychiatry, Box 8134
>> > 660 South Euclid Ave. Tel: 314-747-6173
>> > St. Louis, MO  63110 Email: [email protected]<mailto:[email protected]>
>> >
>> > From: Vishal Patel <[email protected]<mailto:[email protected]>>
>> > Date: Wednesday, November 4, 2015 1:42 PM
>> > To: "[email protected]<mailto:[email protected]
>> >"
>> > <[email protected]<mailto:[email protected]>>
>> > Subject: [HCP-Users] Hcp Data with non-overlapping parcellations
>> >
>> > Hi,
>> >
>> > Does anyone have access to HCP data that has been parcellated in
>> > non-overlapping regions or can point me in the right direction?
>> >
>> > Thanks,
>> >
>> > Vishal
>>
>
> --
> *Matthew George Liptrot*
>
> <http://about.me/matthewliptrot>
> *Department of Computer Science*
> *University of Copenhagen*
> &
> *Section for Cognitive Systems*
> *Department of Applied Mathematics and Computer Science*
> *Technical University of Denmark*
>
> http://about.me/matthewliptrot
>
> <http://about.me/matthewliptrot>
>

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