It’s less RAM-intensive since you only need to load one timeseries at a time.

--Greg

____________________________________________________________________
Greg Burgess, Ph.D.
Staff Scientist, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology
Phone: 314-362-7864
Email: [email protected]

> On Nov 24, 2015, at 12:29 PM, Glasser, Matthew <[email protected]> wrote:
> 
> I'm not sure what benefit you'd get from averaging the FCs across runs within 
> a subject.  That just sounds more computationally intensive.
> 
> Peace,
> 
> Matt.
> 
> 
> From: Joelle Zimmermann <[email protected]>
> Sent: Tuesday, November 24, 2015 11:55 AM
> To: Glasser, Matthew
> Cc: Greg Burgess; Elam, Jennifer; [email protected]
> Subject: Re: [HCP-Users] Phase Encoding left-to-right and right-to-left
>  
> Hi Matt,
> 
> Glad you do point that out, because I was previously looking at the Resting 
> State fMRI 1 Preprocessed, but the Resting State fMRI FIX-Denoised (Compact) 
> is readily available. So I guess for that all I'll need to do is demean and 
> variance normalize, and/or average the two FCs.
> 
> Thanks,
> Joelle
> 
> On Tue, Nov 24, 2015 at 12:19 PM, Glasser, Matthew <[email protected]> wrote:
> Indeed I was assuming you were using FIX cleaned data.  I wouldn't recommend 
> not using FIX cleaned data unless you are testing other clean up approaches.
> 
> Peace,
> 
> Matt.
> ________________________________________
> From: Joelle Zimmermann [[email protected]]
> Sent: Tuesday, November 24, 2015 11:14 AM
> To: Greg Burgess
> Cc: Glasser, Matthew; Elam, Jennifer; [email protected]
> Subject: Re: [HCP-Users] Phase Encoding left-to-right and right-to-left
> 
> Hi Greg,
> 
> Thanks for your response. Indeed, I was considering that myself, to compute 
> the FCs separately and average the LR and RL.
> 
> Thanks,
> Joelle
> 
> On Tue, Nov 24, 2015 at 11:56 AM, Greg Burgess 
> <[email protected]<mailto:[email protected]>> wrote:
> Hi Joelle,
> 
> In addition to demeaning and possibly variance normalization, it is probably 
> a good idea to detrend each run separately using a linear detrend or a high 
> pass filter before concatenation. (FIX-preprocessed data already includes a 
> 2000s high pass filter.)
> 
> Another option that is not described on the wiki (yet) is to compute 
> correlations separately for each run, and then average the Fisher’s 
> z-transformed correlation coefficients, or treat the multiple runs as 
> within-subjects repeated measures.
> 
> --Greg
> 
> ____________________________________________________________________
> Greg Burgess, Ph.D.
> Staff Scientist, Human Connectome Project
> Washington University School of Medicine
> Department of Anatomy and Neurobiology
> Phone: 314-362-7864<tel:314-362-7864>
> Email: [email protected]<mailto:[email protected]>
> 
> > On Nov 23, 2015, at 4:40 PM, Glasser, Matthew 
> > <[email protected]<mailto:[email protected]>> wrote:
> >
> > It doesn’t matter what order you concatenate the data in, but I would not 
> > recommend only analyzing the data of one phase encoding direction.
> >
> > Peace,
> >
> > Matt.
> >
> > From: 
> > <[email protected]<mailto:[email protected]>>
> >  on behalf of Joelle Zimmermann 
> > <[email protected]<mailto:[email protected]>>
> > Date: Monday, November 23, 2015 at 12:48 PM
> > To: "Elam, Jennifer" <[email protected]<mailto:[email protected]>>
> > Cc: "[email protected]<mailto:[email protected]>" 
> > <[email protected]<mailto:[email protected]>>
> > Subject: Re: [HCP-Users] Phase Encoding left-to-right and right-to-left
> >
> > Hi Jennifer and Matt,
> >
> > Thanks for your help. I have a few clarification questions below:
> > Does it matter in which order I concatenate the LR and the RL .nii's? My 
> > ultimate goal is to create a functional connectivity matrix from the time 
> > series.
> > #3 in the link you sent describes that there are 4 runs per subject. Is 
> > this the REST 1, and REST 2, each with LR and RL phase encoding directions?
> > Would using only one phase encoding direction (i.e. do analysis on LR) 
> > expect to effect the results?
> >
> > Thanks,
> > Joelle
> >
> > On Mon, Nov 23, 2015 at 1:17 PM, Jennifer Elam 
> > <[email protected]<mailto:[email protected]>> wrote:
> >> #3 on https://wiki.humanconnectome.org/display/PublicData/HCP+Users+FAQ 
> >> may be of help.
> >>
> >> Best,
> >> Jenn
> >>
> >> Jennifer Elam, Ph.D.
> >> Outreach Coordinator, Human Connectome Project
> >> Washington University School of Medicine
> >> Department of Anatomy and Neurobiology, Box 8108
> >> 660 South Euclid Avenue
> >> St. Louis, MO 63110
> >> 314-362-9387<tel:314-362-9387>
> >> [email protected]<mailto:[email protected]>
> >> www.humanconnectome.org<http://www.humanconnectome.org>
> >>
> >> From:[email protected]<mailto:from%[email protected]>
> >>  
> >> [mailto:[email protected]<mailto:[email protected]>]
> >>  On Behalf Of Glasser, Matthew
> >> Sent: Monday, November 23, 2015 12:16 PM
> >> To: Joelle Zimmermann; 
> >> [email protected]<mailto:[email protected]>
> >> Subject: Re: [HCP-Users] Phase Encoding left-to-right and right-to-left
> >>
> >>
> >>
> >> Usually you concatenate them temporally after demeaning (and perhaps 
> >> variance normalizing).
> >>
> >>
> >>
> >> Peace,
> >>
> >>
> >>
> >> Matt.
> >>
> >>
> >>
> >> From:[email protected]<mailto:from%[email protected]>
> >>  
> >> <[email protected]<mailto:[email protected]>>
> >>  on behalf of Joelle Zimmermann 
> >> <[email protected]<mailto:[email protected]>>
> >> Sent: Monday, November 23, 2015 11:33 AM
> >> To: [email protected]<mailto:[email protected]>
> >> Subject: [HCP-Users] Phase Encoding left-to-right and right-to-left
> >>
> >>
> >>
> >> Hi all,
> >>
> >>
> >>
> >> Would anyone be able to explain a bit more about the phase-encoding 
> >> directions LR and RL for the (preprocessed) REST1 session data from 500 
> >> subjects +MEG2? I understand that LR is left to right and RL is right to 
> >> left.
> >>
> >>
> >>
> >> I'm wondering, are these meant to be somehow combined, or is only one of 
> >> these typically chosen?
> >>
> >>
> >>
> >> Thanks,
> >>
> >> Joelle
> >>
> >>
> >>
> >>
> >>
> >> http://www.humanconnectome.org/documentation/Q1/data-in-this-release.html
> >>
> >> Q1 Data Release: About the Dataset | Human Connectome Project
> >> 76 healthy adult subjects in the age range 22 – 35 participated in the 
> >> first quarter of data collection. These include 68 subjects with data from 
> >> all or nearly all ...
> >> Read more...
> >>
> >>
> >> _______________________________________________
> >> HCP-Users mailing list
> >> [email protected]<mailto:[email protected]>
> >> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
> >>
> >> _______________________________________________
> >> HCP-Users mailing list
> >> [email protected]<mailto:[email protected]>
> >> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
> >>
> >
> > _______________________________________________
> > HCP-Users mailing list
> > [email protected]<mailto:[email protected]>
> > http://lists.humanconnectome.org/mailman/listinfo/hcp-users
> > _______________________________________________
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> > [email protected]<mailto:[email protected]>
> > http://lists.humanconnectome.org/mailman/listinfo/hcp-users
> 
> 
> 
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