Is this a question about the main HCP pipelines or the MEG pipelines?

Matt.

On 8/5/16, 12:24 PM, "[email protected] on behalf of
Demiral, Sukru (NIH/NIAAA) [F]" <[email protected] on
behalf of [email protected]> wrote:

>
>Hi all,
>
>I have two questions related to anatomy pipeline. There are a number of
>wmparc and aseg files in the output of the anatomy pipeline. Is there a
>description of which processes these wmparc files went through? I
>understand that some are normalized to the standard brain and some are
>intensity normalized, I am a bit confused. I just need to use original
>anatomical space wmparc. Same thing for the aseg results. If anyone can
>drop a line or point a documentation that would be great. Thanks,
>
>Baris
>-----Original Message-----
>From: [email protected]
>[mailto:[email protected]]
>Sent: Friday, August 05, 2016 1:00 PM
>To: [email protected]
>Subject: HCP-Users Digest, Vol 45, Issue 5
>
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>
>Today's Topics:
>
>   1. Re: Movement Confounds and Censoring (Michael F.W. Dreyfuss)
>   2. Re: Extracting Power parcellations from
>      RSN-networks.32k_fs_LR (Timothy Coalson)
>   3. Re: Movement Confounds and Censoring (Glasser, Matthew)
>   4. Re: Movement Confounds and Censoring (Glasser, Matthew)
>   5. Re: Extracting Power parcellations from
>      RSN-networks.32k_fs_LR (Salim Arslan)
>
>
>----------------------------------------------------------------------
>
>Message: 1
>Date: Thu, 4 Aug 2016 23:15:30 +0000
>From: "Michael F.W. Dreyfuss" <[email protected]>
>Subject: Re: [HCP-Users] Movement Confounds and Censoring
>To: "Burgess, Gregory" <[email protected]>
>Cc: "[email protected]" <[email protected]>
>Message-ID:
><dm5pr06mb2713c8694ae7bc2c4b283d34fc...@dm5pr06mb2713.namprd06.prod.outlo
>ok.com>
>
>Content-Type: text/plain; charset="windows-1252"
>
>Thank you. On a practical note, if I want to include both motion
>regressors and time points censoring with a censor file I produce for
>each run how can I do that? I am refering specifically to the following
>chunk of code:
>
>
>#Create design files, model confounds if desired
>
>DIR=`pwd`
>
>cd ${FEATDir}
>
>if [ $Confound = "NONE" ] ; then
>
>  feat_model ${FEATDir}/design
>
>else
>
>  feat_model ${FEATDir}/design
>${ResultsFolder}/${LevelOnefMRIName}/${Confound}
>
>fi
>
>cd $DIR
>
>
>When I change that to the code below including another argument for
>thecensor file, the result is the same as if I added no confound (it
>ignores both arguments):
>
>
>feat_model ${FEATDir}/design
>${ResultsFolder}/${LevelOnefMRIName}/${Confound}
>${ResultsFolder}/${LevelOnefMRIName}/censor.txt
>
>
>How can I include both motion regression and censoring files in the
>design files using feat_model or another command?
>
>
>Thank you,
>
>Michael
>
>________________________________
>From: Burgess, Gregory <[email protected]>
>Sent: Thursday, August 4, 2016 10:35:33 AM
>To: Michael F.W. Dreyfuss
>Cc: [email protected]
>Subject: Re: [HCP-Users] Movement Confounds and Censoring
>
>> On Aug 4, 2016, at 8:52 AM, Michael F.W. Dreyfuss
>><[email protected]> wrote:
>>
>> Thank you,
>>
>> Is it recommended to use the motion regressors with or without
>>detrending on data that has been processed with the HCP preprocessing
>>scripts?
>
>You should perform the same filtering on your confound regressors (and
>task model) that you are performing on your data. So, I?d start with the
>original Movement_Regressors.txt.
>
>
>> Is there a recommended cutoff for censoring time points or a
>>recommended threshold of mean relative displacement for excluding a
>>subject or run?
>
>One of the interesting difficulties with HCP data (and occasionally other
>MB fMRI data from other groups) is that motion parameters from MB data
>pick up on some source of variability that is not typically visible in
>motion parameters estimated from fMRI data with lower spatial and
>temporal resolution. So, censoring thresholds that are typical in lower
>resolution fMRI might result in censoring a considerable proportion of
>your data. You might want to look at DVARS to see if it can detect
>apparent motion artifact more cleanly.
>
>Either way, the best strategy is to look at your data to set your own
>threshold. (Look at strategies from Power, J. D., Mitra, A., Laumann, T.
>O., Snyder, A. Z., Schlaggar, B. L., & Petersen, S. E. (2014). Methods to
>detect, characterize, and remove motion artifact in resting state fMRI.
>NeuroImage, 84, 320?341.
>https://urldefense.proofpoint.com/v2/url?u=http-3A__doi.org_10.1016_j.neur
>oimage.2013.08.048&d=DQIF-g&c=lb62iw4YL4RFalcE2hQUQealT9-RXrryqt9KZX2qu2s&
>r=rPclmYysc_z1plf99IoNsmxWf1JolkKMmL6bXnYFSwg&m=rA5E466xAGA4eFveDcDcOazqcX
>IKVYINMcieo_qUh1o&s=W83s5PHORheYaI8ov_xC8VSiKFk3nw9qHj8Q2IvgnNg&e= )
>
>
>> I installed FIX and can implement it on my data, but I can only have it
>>trained to data from your scanners at Wash U since I do not have enough
>>additional data from our scanner here to train it on, so I do not feel
>>comfortable using it on my data.
>
>You could consider hand categorizing the ICA components, if you feel
>comfortable making those judgments and you don?t have tons of data. There
>are also some other automated approaches such as AROMA that have become
>popular with folks. I have no experience with AROMA yet, but I?d imagine
>that it would rate spike-like ICA components as noise.
>
>
>--Greg
>
>____________________________________________________________________
>Greg Burgess, Ph.D.
>Staff Scientist, Human Connectome Project Washington University School of
>Medicine Department of Psychiatry
>Phone: 314-362-7864
>Email: [email protected]
>
>>
>> Thank you,
>> Michael
>> From: Burgess, Gregory <[email protected]>
>> Sent: Tuesday, August 2, 2016 2:30:10 PM
>> To: Michael F.W. Dreyfuss
>> Cc: [email protected]
>> Subject: Re: [HCP-Users] Movement Confounds and Censoring
>>
>> > On Aug 2, 2016, at 10:17 AM, Michael F.W. Dreyfuss
>><[email protected]> wrote:
>>
>> >
>>
>> > Hi, I have some basic questions about the movement parameters that
>>are put out by the HCP preprocessing scripts.
>>
>> >
>>
>> > 1) What is the difference between Movement_Regressors_dt.txt and
>>Movement_Regressors.txt? I would like to use one as a confound.
>>
>>
>>
>> The Movement_Regressors.txt are the parameters computed from the motion
>>correction algorithm. The Movement_Regressors_dt.txt is the same file
>>put through a detrend command to remove the linear trend and mean.
>>
>>
>>
>> >
>>
>> > 2) What does each column in these represent? I'm assuming 6
>>directions of displacement, and 3 for rotation?
>>
>>
>>
>> The 12 columns represent Displacement {x, y, z}, Rotation {x, y, z},
>> Backward Derivative of Displacement {x, y, z}, and Backward Derivative
>> of Rotation {x, y, z}
>>
>>
>>
>> >
>>
>> > 3) What are the units in these and the other movement files in the
>>output? mm? voxels?
>>
>>
>>
>> The units are mm for displacements and degrees for rotations.
>>
>>
>>
>> >
>>
>> > 4) I would like to censor time points with too much motion in
>>Movement_AbsoluteRMS.txt. Is there a specific movement cutoff you
>>recommend? I have made a script that produces a censor file in the fsl
>>format (i.e. columns of all 0s with a 1 at the time point that is
>>censored). Is there a simple way to add that censor file into the
>>existing analysis scripts along with the motion as a confound?
>>
>>
>>
>> First, I would suggest using the Movement_RelativeRMS.txt file for
>>censoring instead. The AbsoluteRMS reflects the total movement from the
>>motion correlation registration target, which is the SBRef volume
>>collected at the beginning of the scan. In contrast, the RelativeRMS
>>reflects the amount of motion from the previous time point, which should
>>be considered a more direct measurement of movement on that specific
>>time point.
>>
>>
>>
>> I?m not sure to which existing analysis scripts you are referring. We
>>don?t release analyses of individual scans. So, you should probably
>>include these censoring confounds as covariates in whatever
>>preprocessing you?re doing for the individual scans.
>>
>>
>>
>> After saying all of that, it is worth mentioning that FIX denoising:
>>
>> - Regresses a set of 24 motion parameters (six rigid body parameters,
>> their backward derivatives, and the squares of those 12 columns)
>>
>> - Regresses noise component variance (orthogonal to signal components)
>>from the scan-level ICA.
>>
>>
>>
>> In practice, the behavior of FIX is similar to regressing movement
>>paremeters and voxel-specific censoring (plus other artifact cleanup).
>>If you utilize FIX preprocessed data, you don?t need to regress motion
>>parameters, and you might feel comfortable skipping censoring as well.
>>
>>
>>
>> --Greg
>>
>>
>>
>> ____________________________________________________________________
>>
>> Greg Burgess, Ph.D.
>>
>> Staff Scientist, Human Connectome Project
>>
>> Washington University School of Medicine
>>
>> Department of Psychiatry
>>
>> Phone: 314-362-7864
>>
>> Email: [email protected]
>>
>>
>>
>>
>>
>> >
>>
>> > Thank you,
>>
>> > Michael
>>
>> > _______________________________________________
>>
>> > HCP-Users mailing list
>>
>> > [email protected]
>>
>> > https://urldefense.proofpoint.com/v2/url?u=http-3A__lists.humanconne
>> > ctome.org_mailman_listinfo_hcp-2Dusers&d=DQIGaQ&c=lb62iw4YL4RFalcE2h
>> > QUQealT9-RXrryqt9KZX2qu2s&r=rPclmYysc_z1plf99IoNsmxWf1JolkKMmL6bXnYF
>> > Swg&m=FMg6DAhRQHwDPdwDze2CIg4j1-kMkVc9h-XJ0PXmDWQ&s=ck-KAIP80cxbdHtG
>> > 0fMXtiT8T_-4QzuQ-lNVQlPrDs8&e=
>>
>>
>>
>>
>>
>>
>>
>>
>>
>> ________________________________
>>
>> The materials in this message are private and may contain Protected
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>
>________________________________
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>------------------------------
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>Message: 2
>Date: Thu, 4 Aug 2016 18:46:14 -0500
>From: Timothy Coalson <[email protected]>
>Subject: Re: [HCP-Users] Extracting Power parcellations from
>RSN-networks.32k_fs_LR
>To: Salim Arslan <[email protected]>
>Cc: "[email protected]" <[email protected]>
>Message-ID:
><CAK_=taz7ftv6uk3_59io7ugbdlzzmu_c_f1x+ngbprc_ty6...@mail.gmail.com>
>Content-Type: text/plain; charset="utf-8"
>
>Using -cifti-separate on the original cifti file and viewing in wb_view
>looks identical to the original.  However, I think I see what is going
>on, after getting a hint from the way you reset the color scheme - the
>file has
>2 labels named "a3_Default_mode", and similar for other labels, and
>turning one of them off reveals these holes.
>
>What has happened is that someone has set the names and colors of two
>label values to be identical (except for a space on the end of one, to
>slip past the uniqueness tests on the label names), but they are actually
>different integers in those patches.  I don't know how this happened, as
>map 4 doesn't have this difference in values.  We should probably fix
>this in the data file.
>
>Tim
>
>
>On Thu, Aug 4, 2016 at 3:44 AM, Salim Arslan <[email protected]>
>wrote:
>
>> Hi Tim,
>>
>> Thanks for your attention.
>>
>> After your message, I also thought the problem was about the order of
>> the hemisphere in the cifti file. However, after running wb_command
>> -file-information -no-map-info I can confirm that the order is correct.
>> Here is the output:
>>
>> Name:                    RSN-networks.32k_fs_LR.dlabel.nii
>> Type:                    Connectivity - Dense Label
>> Structure:               CortexLeft CortexRight
>> Data Size:               1.04 Megabytes
>> Maps to Surface:         true
>> Maps to Volume:          false
>> Maps with LabelTable:    true
>> Maps with Palette:       false
>> Number of Rows:          64984
>> Number of Columns:       4
>> Volume Dim[0]:           0
>> Volume Dim[1]:           0
>> Volume Dim[2]:           0
>> Palette Type:            None
>> CIFTI Dim[0]:            4
>> CIFTI Dim[1]:            64984
>> ALONG_ROW map type:      LABELS
>> ALONG_COLUMN map type:   BRAIN_MODELS
>>     Has Volume Data:     false
>>     CortexLeft:          32492 out of 32492 vertices
>>     CortexRight:         32492 out of 32492 vertices
>>
>>
>> I do not think anotherCii has also nothing to do with this, as it is
>> just a cii file with the same row dimensionality (64984x1).
>>
>> Following the suggestion in your other message, I have extracted the
>> hemisphere-specific full-surface label files using wb_command
>> -cifti-separate with the -label repeatable option and saved the output
>> in a gii file. The result was the same.
>>
>> One thing I forgot to mention and might be important is that, among 4
>> parcellations stored in RSN-networks.32k_fs_LR.dlbal.nii, only the
>> holes-filled power labels (3rd column) has this problem. The others
>> are just fine. This also makes me think that dlabel file, at least
>> partly, was generated in an unusual way. Perhaps someone involved in
>> the generation of the tutorial data package or the aforementioned
>> BALSA study can shed light on this.
>>
>> Salim
>>
>>
>>
>> ------------------------------
>> *From:* Timothy Coalson <[email protected]>
>> *To:* Salim Arslan <[email protected]>
>> *Cc:* "[email protected]" <[email protected]>
>> *Sent:* Wednesday, August 3, 2016 9:36 PM
>> *Subject:* Re: [HCP-Users] Extracting Power parcellations from
>> RSN-networks.32k_fs_LR
>>
>> First, the size of 64984 shows that the cifti file in question did not
>> have the medial wall masked out internally, which is likely the
>> starting point for these problems.  I don't know how medialMask is
>> defined, but if it isn't 32492 elements long (in this case), then that
>> will cause another problem, as the break between left and right data
>> will be in the wrong place.
>>
>> If you really didn't do any steps between defining labelsL and
>> labelsR, and anotherCii was made as a copy of that same cii variable,
>> then I don't know how it managed to mess things up, though, unless
>> this cifti file also managed to have right hemisphere before left
>> hemisphere (the format supports this, but we have tried to be
>> consistent with the order - the lack of a medial wall mask indicates
>> this dlabel file was generated in an unusual way, though).  You can
>> use "wb_command -file-information -no-map-info" to see the order of
>>structures in the cifti file.
>>
>> Tim
>>
>>
>> On Wed, Aug 3, 2016 at 11:22 AM, Salim Arslan <[email protected]>
>> wrote:
>>
>> Hello,
>>
>> I am trying to get Power parcellations out of
>> RSN-networks.32k_fs_LR.dlabel.nii, that comes with the "Brain Analysis
>> Library of Spatial maps and Atlases (BALSA) database study" (
>> https://balsa.wustl.edu/study/show/WG33). It is also part of the
>> tutorial dataset.
>>
>> I did what I have been always doing for extracting data from CIFTI
>> files in Matlab. Using ciftiopen, I obtained the cii object, which in
>> this case, contains the cdata matrix of size 64984x4. The 3rd column
>> here corresponds to the holes-filled Power parcellations. To extract
>> those for both hemispheres, I simply split up the 64984 vector and
>> masked out the medial wall vertices and then saved the labels back to
>>CIFTI.
>>
>> cii = ciftiopen('RSN-networks.32k_fs_LR.dlabel.nii', wb_command);
>> cdata = cii.cdata; parcellation = cdata(:,3); labelsL =
>> cifti(1:length(medialMask)); labelsR =
>> cifti(length(medialMask)+1:end); anotherCii.cdata = [labelsL;labelsR];
>> ciftisave(anotherCii,'power.dlabel.nii',wb_command)
>>
>> However when I visualized the labels on workbench, I noticed some
>> holes (with random labels) in many parcels. Please see the attached
>> figure for clarification.
>>
>> I assume this is something to do with the medial masking, but cannot
>> figure out what is wrong. Any help is appreciated.
>>
>> Thanks for your attention.
>>
>> Best regards,
>> Salim
>>
>> --
>> _______________________________________________
>> HCP-Users mailing list
>> [email protected]
>> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>>
>>
>>
>>
>>
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>------------------------------
>
>Message: 3
>Date: Fri, 5 Aug 2016 00:21:22 +0000
>From: "Glasser, Matthew" <[email protected]>
>Subject: Re: [HCP-Users] Movement Confounds and Censoring
>To: "Burgess, Gregory" <[email protected]>, "Michael F.W. Dreyfuss"
><[email protected]>
>Cc: "[email protected]" <[email protected]>
>Message-ID: <d3c945f8.1224c3%[email protected]>
>Content-Type: text/plain; charset="iso-8859-1"
>
>If you are acquiring HCP-style data, it would probably be fine to use
>ICA+FIX based on HCP training.
>
>Matt.
>
>On 8/4/16, 9:35 AM, "[email protected] on behalf of
>Burgess, Gregory" <[email protected] on behalf of
>[email protected]> wrote:
>
>>> On Aug 4, 2016, at 8:52 AM, Michael F.W. Dreyfuss
>>><[email protected]> wrote:
>>>
>>> Thank you,
>>>
>>> Is it recommended to use the motion regressors with or without
>>>detrending on data that has been processed with the HCP preprocessing
>>>scripts?
>>
>>You should perform the same filtering on your confound regressors (and
>>task model) that you are performing on your data. So, I?d start with
>>the original Movement_Regressors.txt.
>>
>>
>>> Is there a recommended cutoff for censoring time points or a
>>>recommended threshold of mean relative displacement for excluding a
>>>subject or run?
>>
>>One of the interesting difficulties with HCP data (and occasionally
>>other MB fMRI data from other groups) is that motion parameters from MB
>>data pick up on some source of variability that is not typically
>>visible in motion parameters estimated from fMRI data with lower
>>spatial and temporal resolution. So, censoring thresholds that are
>>typical in lower resolution fMRI might result in censoring a
>>considerable proportion of your data. You might want to look at DVARS
>>to see if it can detect apparent motion artifact more cleanly.
>>
>>Either way, the best strategy is to look at your data to set your own
>>threshold. (Look at strategies from Power, J. D., Mitra, A., Laumann, T.
>>O., Snyder, A. Z., Schlaggar, B. L., & Petersen, S. E. (2014). Methods
>>to detect, characterize, and remove motion artifact in resting state
>>fMRI.
>>NeuroImage, 84, 320?341.
>>http://doi.org/10.1016/j.neuroimage.2013.08.048)
>>
>>
>>> I installed FIX and can implement it on my data, but I can only have
>>>it trained to data from your scanners at Wash U since I do not have
>>>enough additional data from our scanner here to train it on, so I do
>>>not feel comfortable using it on my data.
>>
>>You could consider hand categorizing the ICA components, if you feel
>>comfortable making those judgments and you don?t have tons of data.
>>There are also some other automated approaches such as AROMA that have
>>become popular with folks. I have no experience with AROMA yet, but I?d
>>imagine that it would rate spike-like ICA components as noise.
>>
>>
>>--Greg
>>
>>____________________________________________________________________
>>Greg Burgess, Ph.D.
>>Staff Scientist, Human Connectome Project Washington University School
>>of Medicine Department of Psychiatry
>>Phone: 314-362-7864
>>Email: [email protected]
>>
>>>
>>> Thank you,
>>> Michael
>>> From: Burgess, Gregory <[email protected]>
>>> Sent: Tuesday, August 2, 2016 2:30:10 PM
>>> To: Michael F.W. Dreyfuss
>>> Cc: [email protected]
>>> Subject: Re: [HCP-Users] Movement Confounds and Censoring
>>>
>>> > On Aug 2, 2016, at 10:17 AM, Michael F.W. Dreyfuss
>>><[email protected]> wrote:
>>>
>>> >
>>>
>>> > Hi, I have some basic questions about the movement parameters that
>>>are put out by the HCP preprocessing scripts.
>>>
>>> >
>>>
>>> > 1) What is the difference between Movement_Regressors_dt.txt and
>>>Movement_Regressors.txt? I would like to use one as a confound.
>>>
>>>
>>>
>>> The Movement_Regressors.txt are the parameters computed from the
>>>motion correction algorithm. The Movement_Regressors_dt.txt is the
>>>same file put through a detrend command to remove the linear trend and
>>>mean.
>>>
>>>
>>>
>>> >
>>>
>>> > 2) What does each column in these represent? I'm assuming 6
>>>directions of displacement, and 3 for rotation?
>>>
>>>
>>>
>>> The 12 columns represent Displacement {x, y, z}, Rotation {x, y, z},
>>>Backward Derivative of Displacement {x, y, z}, and Backward Derivative
>>>of Rotation {x, y, z}
>>>
>>>
>>>
>>> >
>>>
>>> > 3) What are the units in these and the other movement files in the
>>>output? mm? voxels?
>>>
>>>
>>>
>>> The units are mm for displacements and degrees for rotations.
>>>
>>>
>>>
>>> >
>>>
>>> > 4) I would like to censor time points with too much motion in
>>>Movement_AbsoluteRMS.txt. Is there a specific movement cutoff you
>>>recommend? I have made a script that produces a censor file in the fsl
>>>format (i.e. columns of all 0s with a 1 at the time point that is
>>>censored). Is there a simple way to add that censor file into the
>>>existing analysis scripts along with the motion as a confound?
>>>
>>>
>>>
>>> First, I would suggest using the Movement_RelativeRMS.txt file for
>>>censoring instead. The AbsoluteRMS reflects the total movement from
>>>the motion correlation registration target, which is the SBRef volume
>>>collected at the beginning of the scan. In contrast, the RelativeRMS
>>>reflects the amount of motion from the previous time point, which
>>>should be considered a more direct measurement of movement on that
>>>specific time point.
>>>
>>>
>>>
>>> I?m not sure to which existing analysis scripts you are referring. We
>>>don?t release analyses of individual scans. So, you should probably
>>>include these censoring confounds as covariates in whatever
>>>preprocessing you?re doing for the individual scans.
>>>
>>>
>>>
>>> After saying all of that, it is worth mentioning that FIX denoising:
>>>
>>> - Regresses a set of 24 motion parameters (six rigid body parameters,
>>>their backward derivatives, and the squares of those 12 columns)
>>>
>>> - Regresses noise component variance (orthogonal to signal
>>>components) from the scan-level ICA.
>>>
>>>
>>>
>>> In practice, the behavior of FIX is similar to regressing movement
>>>paremeters and voxel-specific censoring (plus other artifact cleanup).
>>>If you utilize FIX preprocessed data, you don?t need to regress motion
>>>parameters, and you might feel comfortable skipping censoring as well.
>>>
>>>
>>>
>>> --Greg
>>>
>>>
>>>
>>> ____________________________________________________________________
>>>
>>> Greg Burgess, Ph.D.
>>>
>>> Staff Scientist, Human Connectome Project
>>>
>>> Washington University School of Medicine
>>>
>>> Department of Psychiatry
>>>
>>> Phone: 314-362-7864
>>>
>>> Email: [email protected]
>>>
>>>
>>>
>>>
>>>
>>> >
>>>
>>> > Thank you,
>>>
>>> > Michael
>>>
>>> > _______________________________________________
>>>
>>> > HCP-Users mailing list
>>>
>>> > [email protected]
>>>
>>> >
>>>https://urldefense.proofpoint.com/v2/url?u=http-3A__lists.humanconnect
>>>ome
>>>.org_mailman_listinfo_hcp-2Dusers&d=DQIGaQ&c=lb62iw4YL4RFalcE2hQUQealT
>>>9-R
>>>Xrryqt9KZX2qu2s&r=rPclmYysc_z1plf99IoNsmxWf1JolkKMmL6bXnYFSwg&m=FMg6DA
>>>hRQ
>>>HwDPdwDze2CIg4j1-kMkVc9h-XJ0PXmDWQ&s=ck-KAIP80cxbdHtG0fMXtiT8T_-4QzuQ-
>>>lNV
>>>QlPrDs8&e=
>>>
>>>
>>>
>>>
>>>
>>>
>>>
>>>
>>>
>>> ________________________________
>>>
>>> The materials in this message are private and may contain Protected
>>>Healthcare Information or other information of a sensitive nature. If
>>>you are not the intended recipient, be advised that any unauthorized
>>>use, disclosure, copying or the taking of any action in reliance on
>>>the contents of this information is strictly prohibited. If you have
>>>received this email in error, please immediately notify the sender via
>>>telephone or return mail.
>>>
>>
>>
>>
>>________________________________
>>The materials in this message are private and may contain Protected
>>Healthcare Information or other information of a sensitive nature. If
>>you are not the intended recipient, be advised that any unauthorized
>>use, disclosure, copying or the taking of any action in reliance on the
>>contents of this information is strictly prohibited. If you have
>>received this email in error, please immediately notify the sender via
>>telephone or return mail.
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>
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>________________________________
>The materials in this message are private and may contain Protected
>Healthcare Information or other information of a sensitive nature. If you
>are not the intended recipient, be advised that any unauthorized use,
>disclosure, copying or the taking of any action in reliance on the
>contents of this information is strictly prohibited. If you have received
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>
>Message: 4
>Date: Fri, 5 Aug 2016 00:24:19 +0000
>From: "Glasser, Matthew" <[email protected]>
>Subject: Re: [HCP-Users] Movement Confounds and Censoring
>To: "Michael F.W. Dreyfuss" <[email protected]>, "Burgess,
>Gregory"<[email protected]>
>Cc: "[email protected]" <[email protected]>
>Message-ID: <d3c946cf.1224cc%[email protected]>
>Content-Type: text/plain; charset="windows-1252"
>
>You probably need to merge the files using something like paste.
>
>Peace,
>
>Matt.
>
>From:
><[email protected]<mailto:hcp-users-bounces@humanconne
>ctome.org>> on behalf of "Michael F.W. Dreyfuss"
><[email protected]<mailto:[email protected]>>
>Date: Thursday, August 4, 2016 at 6:15 PM
>To: "Burgess, Gregory" <[email protected]<mailto:[email protected]>>
>Cc: "[email protected]<mailto:[email protected]>"
><[email protected]<mailto:[email protected]>>
>Subject: Re: [HCP-Users] Movement Confounds and Censoring
>
>
>Thank you. On a practical note, if I want to include both motion
>regressors and time points censoring with a censor file I produce for
>each run how can I do that? I am refering specifically to the following
>chunk of code:
>
>
>#Create design files, model confounds if desired
>
>DIR=`pwd`
>
>cd ${FEATDir}
>
>if [ $Confound= "NONE"] ;then
>
>  feat_model ${FEATDir}/design
>
>else
>
>  feat_model ${FEATDir}/design
>${ResultsFolder}/${LevelOnefMRIName}/${Confound}
>
>fi
>
>cd $DIR
>
>
>When I change that to the code below including another argument for
>thecensor file, the result is the same as if I added no confound (it
>ignores both arguments):
>
>
>feat_model ${FEATDir}/design
>${ResultsFolder}/${LevelOnefMRIName}/${Confound}
>${ResultsFolder}/${LevelOnefMRIName}/censor.txt
>
>
>How can I include both motion regression and censoring files in the
>design files using feat_model or another command?
>
>
>Thank you,
>
>Michael
>
>________________________________
>From: Burgess, Gregory <[email protected]<mailto:[email protected]>>
>Sent: Thursday, August 4, 2016 10:35:33 AM
>To: Michael F.W. Dreyfuss
>Cc: [email protected]<mailto:[email protected]>
>Subject: Re: [HCP-Users] Movement Confounds and Censoring
>
>> On Aug 4, 2016, at 8:52 AM, Michael F.W. Dreyfuss
>><[email protected]<mailto:[email protected]>> wrote:
>>
>> Thank you,
>>
>> Is it recommended to use the motion regressors with or without
>>detrending on data that has been processed with the HCP preprocessing
>>scripts?
>
>You should perform the same filtering on your confound regressors (and
>task model) that you are performing on your data. So, I?d start with the
>original Movement_Regressors.txt.
>
>
>> Is there a recommended cutoff for censoring time points or a
>>recommended threshold of mean relative displacement for excluding a
>>subject or run?
>
>One of the interesting difficulties with HCP data (and occasionally other
>MB fMRI data from other groups) is that motion parameters from MB data
>pick up on some source of variability that is not typically visible in
>motion parameters estimated from fMRI data with lower spatial and
>temporal resolution. So, censoring thresholds that are typical in lower
>resolution fMRI might result in censoring a considerable proportion of
>your data. You might want to look at DVARS to see if it can detect
>apparent motion artifact more cleanly.
>
>Either way, the best strategy is to look at your data to set your own
>threshold. (Look at strategies from Power, J. D., Mitra, A., Laumann, T.
>O., Snyder, A. Z., Schlaggar, B. L., & Petersen, S. E. (2014). Methods to
>detect, characterize, and remove motion artifact in resting state fMRI.
>NeuroImage, 84, 320?341.
>https://urldefense.proofpoint.com/v2/url?u=http-3A__doi.org_10.1016_j.neur
>oimage.2013.08.048&d=DQIF-g&c=lb62iw4YL4RFalcE2hQUQealT9-RXrryqt9KZX2qu2s&
>r=rPclmYysc_z1plf99IoNsmxWf1JolkKMmL6bXnYFSwg&m=rA5E466xAGA4eFveDcDcOazqcX
>IKVYINMcieo_qUh1o&s=W83s5PHORheYaI8ov_xC8VSiKFk3nw9qHj8Q2IvgnNg&e= )
>
>
>> I installed FIX and can implement it on my data, but I can only have it
>>trained to data from your scanners at Wash U since I do not have enough
>>additional data from our scanner here to train it on, so I do not feel
>>comfortable using it on my data.
>
>You could consider hand categorizing the ICA components, if you feel
>comfortable making those judgments and you don?t have tons of data. There
>are also some other automated approaches such as AROMA that have become
>popular with folks. I have no experience with AROMA yet, but I?d imagine
>that it would rate spike-like ICA components as noise.
>
>
>--Greg
>
>____________________________________________________________________
>Greg Burgess, Ph.D.
>Staff Scientist, Human Connectome Project Washington University School of
>Medicine Department of Psychiatry
>Phone: 314-362-7864
>Email: [email protected]<mailto:[email protected]>
>
>>
>> Thank you,
>> Michael
>> From: Burgess, Gregory <[email protected]<mailto:[email protected]>>
>> Sent: Tuesday, August 2, 2016 2:30:10 PM
>> To: Michael F.W. Dreyfuss
>> Cc:
>> [email protected]<mailto:[email protected]>
>> Subject: Re: [HCP-Users] Movement Confounds and Censoring
>>
>> > On Aug 2, 2016, at 10:17 AM, Michael F.W. Dreyfuss
>><[email protected]<mailto:[email protected]>> wrote:
>>
>> >
>>
>> > Hi, I have some basic questions about the movement parameters that
>>are put out by the HCP preprocessing scripts.
>>
>> >
>>
>> > 1) What is the difference between Movement_Regressors_dt.txt and
>>Movement_Regressors.txt? I would like to use one as a confound.
>>
>>
>>
>> The Movement_Regressors.txt are the parameters computed from the motion
>>correction algorithm. The Movement_Regressors_dt.txt is the same file
>>put through a detrend command to remove the linear trend and mean.
>>
>>
>>
>> >
>>
>> > 2) What does each column in these represent? I'm assuming 6
>>directions of displacement, and 3 for rotation?
>>
>>
>>
>> The 12 columns represent Displacement {x, y, z}, Rotation {x, y, z},
>> Backward Derivative of Displacement {x, y, z}, and Backward Derivative
>> of Rotation {x, y, z}
>>
>>
>>
>> >
>>
>> > 3) What are the units in these and the other movement files in the
>>output? mm? voxels?
>>
>>
>>
>> The units are mm for displacements and degrees for rotations.
>>
>>
>>
>> >
>>
>> > 4) I would like to censor time points with too much motion in
>>Movement_AbsoluteRMS.txt. Is there a specific movement cutoff you
>>recommend? I have made a script that produces a censor file in the fsl
>>format (i.e. columns of all 0s with a 1 at the time point that is
>>censored). Is there a simple way to add that censor file into the
>>existing analysis scripts along with the motion as a confound?
>>
>>
>>
>> First, I would suggest using the Movement_RelativeRMS.txt file for
>>censoring instead. The AbsoluteRMS reflects the total movement from the
>>motion correlation registration target, which is the SBRef volume
>>collected at the beginning of the scan. In contrast, the RelativeRMS
>>reflects the amount of motion from the previous time point, which should
>>be considered a more direct measurement of movement on that specific
>>time point.
>>
>>
>>
>> I?m not sure to which existing analysis scripts you are referring. We
>>don?t release analyses of individual scans. So, you should probably
>>include these censoring confounds as covariates in whatever
>>preprocessing you?re doing for the individual scans.
>>
>>
>>
>> After saying all of that, it is worth mentioning that FIX denoising:
>>
>> - Regresses a set of 24 motion parameters (six rigid body parameters,
>> their backward derivatives, and the squares of those 12 columns)
>>
>> - Regresses noise component variance (orthogonal to signal components)
>>from the scan-level ICA.
>>
>>
>>
>> In practice, the behavior of FIX is similar to regressing movement
>>paremeters and voxel-specific censoring (plus other artifact cleanup).
>>If you utilize FIX preprocessed data, you don?t need to regress motion
>>parameters, and you might feel comfortable skipping censoring as well.
>>
>>
>>
>> --Greg
>>
>>
>>
>> ____________________________________________________________________
>>
>> Greg Burgess, Ph.D.
>>
>> Staff Scientist, Human Connectome Project
>>
>> Washington University School of Medicine
>>
>> Department of Psychiatry
>>
>> Phone: 314-362-7864
>>
>> Email: [email protected]<mailto:[email protected]>
>>
>>
>>
>>
>>
>> >
>>
>> > Thank you,
>>
>> > Michael
>>
>> > _______________________________________________
>>
>> > HCP-Users mailing list
>>
>> > [email protected]<mailto:[email protected]>
>>
>> > https://urldefense.proofpoint.com/v2/url?u=http-3A__lists.humanconne
>> > ctome.org_mailman_listinfo_hcp-2Dusers&d=DQIGaQ&c=lb62iw4YL4RFalcE2h
>> > QUQealT9-RXrryqt9KZX2qu2s&r=rPclmYysc_z1plf99IoNsmxWf1JolkKMmL6bXnYF
>> > Swg&m=FMg6DAhRQHwDPdwDze2CIg4j1-kMkVc9h-XJ0PXmDWQ&s=ck-KAIP80cxbdHtG
>> > 0fMXtiT8T_-4QzuQ-lNVQlPrDs8&e=
>>
>>
>>
>>
>>
>>
>>
>>
>>
>> ________________________________
>>
>> The materials in this message are private and may contain Protected
>>Healthcare Information or other information of a sensitive nature. If
>>you are not the intended recipient, be advised that any unauthorized
>>use, disclosure, copying or the taking of any action in reliance on the
>>contents of this information is strictly prohibited. If you have
>>received this email in error, please immediately notify the sender via
>>telephone or return mail.
>>
>
>
>
>________________________________
>The materials in this message are private and may contain Protected
>Healthcare Information or other information of a sensitive nature. If you
>are not the intended recipient, be advised that any unauthorized use,
>disclosure, copying or the taking of any action in reliance on the
>contents of this information is strictly prohibited. If you have received
>this email in error, please immediately notify the sender via telephone
>or return mail.
>
>_______________________________________________
>HCP-Users mailing list
>[email protected]<mailto:[email protected]>
>http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>
>________________________________
>The materials in this message are private and may contain Protected
>Healthcare Information or other information of a sensitive nature. If you
>are not the intended recipient, be advised that any unauthorized use,
>disclosure, copying or the taking of any action in reliance on the
>contents of this information is strictly prohibited. If you have received
>this email in error, please immediately notify the sender via telephone
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>------------------------------
>
>Message: 5
>Date: Fri, 5 Aug 2016 08:27:38 +0000 (UTC)
>From: Salim Arslan <[email protected]>
>Subject: Re: [HCP-Users] Extracting Power parcellations from
>RSN-networks.32k_fs_LR
>To: Timothy Coalson <[email protected]>
>Cc: "[email protected]" <[email protected]>
>Message-ID:
><[email protected]>
>Content-Type: text/plain; charset="utf-8"
>
>Dear Tim,
>Thanks for the follow-up. Could you suggest a quick solution for this
>that can do the work until the release of the fixed data file? I am not
>much familiar with most of the wb_command,- as you can see in my original
>post, I am more of a Matlab person- so perhaps, if you could give me a
>hint about how to change those label files, I would really appreciate. A
>command that can be used for filling the holes in the 4th map in order to
>regenerate the 3rd map would also help.
>Best regards,Salim?
>
>      From: Timothy Coalson <[email protected]>
> To: Salim Arslan <[email protected]>
>Cc: "[email protected]" <[email protected]>
> Sent: Friday, August 5, 2016 12:46 AM
> Subject: Re: [HCP-Users] Extracting Power parcellations from
>RSN-networks.32k_fs_LR
>
>Using -cifti-separate on the original cifti file and viewing in wb_view
>looks identical to the original.? However, I think I see what is going
>on, after getting a hint from the way you reset the color scheme - the
>file has 2 labels named "a3_Default_mode", and similar for other labels,
>and turning one of them off reveals these holes.
>What has happened is that someone has set the names and colors of two
>label values to be identical (except for a space on the end of one, to
>slip past the uniqueness tests on the label names), but they are actually
>different integers in those patches.? I don't know how this happened, as
>map 4 doesn't have this difference in values.? We should probably fix
>this in the data file.
>Tim
>
>On Thu, Aug 4, 2016 at 3:44 AM, Salim Arslan <[email protected]>
>wrote:
>
>Hi Tim,
>Thanks for your attention.
>After your message, I also thought the problem was about the order of the
>hemisphere in the cifti file. However, after running?wb_command
>-file-information -no-map-info I can confirm that the order is correct.
>Here is the output:
>Name: ? ? ? ? ? ? ? ? ? ?RSN-networks.32k_fs_LR. dlabel.niiType: ? ? ? ?
>? ? ? ? ? ?Connectivity - Dense LabelStructure: ? ? ? ? ? ? ? CortexLeft
>CortexRight?Data Size: ? ? ? ? ? ? ? 1.04 MegabytesMaps to Surface: ? ? ?
>? trueMaps to Volume: ? ? ? ? ?falseMaps with LabelTable: ? ?trueMaps
>with Palette: ? ? ? falseNumber of Rows: ? ? ? ? ?64984Number of Columns:
>? ? ? 4Volume Dim[0]: ? ? ? ? ? 0Volume Dim[1]: ? ? ? ? ? 0Volume Dim[2]:
>? ? ? ? ? 0Palette Type: ? ? ? ? ? ?NoneCIFTI Dim[0]: ? ? ? ? ? ?4CIFTI
>Dim[1]: ? ? ? ? ? ?64984ALONG_ROW map type: ? ? ?LABELSALONG_COLUMN map
>type: ? BRAIN_MODELS? ? Has Volume Data: ? ? false? ? CortexLeft: ? ? ? ?
>?32492 out of 32492 vertices? ? CortexRight: ? ? ? ? 32492 out of 32492
>vertices
>
>I do not think anotherCii has also nothing to do with this, as it is just
>a cii file with the same row dimensionality (64984x1).?
>Following the suggestion in your other message, I have extracted the
>hemisphere-specific full-surface label files using wb_command
>-cifti-separate with the -label repeatable option and saved the output in
>a gii file. The result was the same.?
>One thing I forgot to mention and might be important is that, among 4
>parcellations stored in RSN-networks.32k_fs_LR.dlbal. nii, only the
>holes-filled power labels (3rd column) has this problem. The others are
>just fine. This also makes me think that dlabel file, at least ?partly,
>was generated in an unusual way. Perhaps someone involved in the
>generation of the tutorial data package or the aforementioned BALSA study
>can shed light on this.
>Salim?
>
>
>      From: Timothy Coalson <[email protected]>
> To: Salim Arslan <[email protected]>
>Cc: "[email protected] " <[email protected] >
> Sent: Wednesday, August 3, 2016 9:36 PM
> Subject: Re: [HCP-Users] Extracting Power parcellations from
>RSN-networks.32k_fs_LR
>
>First, the size of 64984 shows that the cifti file in question did not
>have the medial wall masked out internally, which is likely the starting
>point for these problems.? I don't know how medialMask is defined, but if
>it isn't 32492 elements long (in this case), then that will cause another
>problem, as the break between left and right data will be in the wrong
>place.
>If you really didn't do any steps between defining labelsL and labelsR,
>and anotherCii was made as a copy of that same cii variable, then I don't
>know how it managed to mess things up, though, unless this cifti file
>also managed to have right hemisphere before left hemisphere (the format
>supports this, but we have tried to be consistent with the order - the
>lack of a medial wall mask indicates this dlabel file was generated in an
>unusual way, though).? You can use "wb_command -file-information
>-no-map-info" to see the order of structures in the cifti file.
>Tim
>
>On Wed, Aug 3, 2016 at 11:22 AM, Salim Arslan <[email protected]>
>wrote:
>
>Hello,
>
>I am trying to get Power parcellations out of
>RSN-networks.32k_fs_LR.dlabel. nii, that comes with the "Brain Analysis
>Library of Spatial maps and Atlases (BALSA) database study"
>(https://balsa.wustl.edu/ study/show/WG33). It is also part of the
>tutorial dataset.
>
>I did what I have been always doing for extracting data from CIFTI files
>in Matlab. Using ciftiopen, I obtained the cii object, which in this
>case, contains the cdata matrix of size 64984x4. The 3rd column here
>corresponds to the holes-filled Power parcellations. To extract those for
>both hemispheres, I simply split up the 64984 vector and masked out the
>medial wall vertices and then saved the labels back to CIFTI.
>
>cii = ciftiopen('RSN-networks.32k_ fs_LR.dlabel.nii', wb_command);?
>cdata = cii.cdata;
>parcellation = cdata(:,3);
>labelsL = cifti(1:length(medialMask));
>labelsR = cifti(length(medialMask)+1: end); anotherCii.cdata =
>[labelsL;labelsR]; ciftisave(anotherCii,'power. dlabel.nii',wb_command)
>
>However when I visualized the labels on workbench, I noticed some holes
>(with random labels) in many parcels. Please see the attached figure for
>clarification.
>
>I assume this is something to do with the medial masking, but cannot
>figure out what is wrong. Any help is appreciated.
>
>Thanks for your attention.?
>Best regards,Salim
>
>--
>______________________________ _________________ HCP-Users mailing list
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>
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