I think duty cycle issues are a bigger deal for long diffusion scans.  I’ll 
note that if this is resting state data subjects may be likely to fall asleep 
with long scans, which will cause significant changes in functional 
connectivity.

Peace,

Matt.

From: 
<[email protected]<mailto:[email protected]>>
 on behalf of "Mark A. Pinsk" <[email protected]<mailto:[email protected]>>
Date: Thursday, October 19, 2017 at 1:48 PM
To: "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>
Subject: [HCP-Users] question re: collecting long duration BOLD EPI scans

Hi all,

We have several investigators here that would like to collect multi band BOLD 
EPI runs of very long duration (~1 hour).

First, we found that the product Siemens SMS sequence limits you to 35 min 47 
sec.  Once your # measurements exceeds that duration, the TA changes to show 
>=24 hours and refuses to run.  Has anyone noticed this or found a workaround?

Second, it appears that the CMRR SMS sequence does not have this limitation.  
So we were planning on recommending that those users who want to collect very 
long EPI runs use the CMRR sequence.

Can we expect increases in thermal noise or any other duty-cycle related issues 
that might reduce SNR progressively over time?  And should we be concerned at 
all about increased wear on the gradient coils or other hardware if we don't 
allow it to cool down more frequently?

Thanks ahead for any advice!
Mark


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