Dear HCP gurus;
I’m writing about step 3 below. I have run some of my own data through the HCP 
pipelines, and they have worked well when I use RegName=“FS”. However, when I 
try to use RegName=“MSMSulc” the script can’t find this file: 
allparameterssulcDRconf
I have been unable to find this file anywhere - not in the Pipelines-master 
directory nor in the MSM_HOCR_v2 directory (downloaded from your link, below).
The MSM_HOCR_v2 directory has the following config files: 
config_MSMsulc_pairwise, configMSMSulc_strain, MSMAll_config_STRAIN, and a file 
of size 0 named allparameterssulcDRconfStage1to4.
Please advise whether I should use one of the alternate files named above, or 
where I can find allparameterssulcDRconf.
Thanks so much,
Sally

On Jun 30, 2017, at 3:19 PM, Glasser, Matthew 
<[email protected]<mailto:[email protected]>> wrote:

You can give MSMSulc and MSMAll a try if you wish using the latest version of 
the HCP pipelines and the MSM binary, which is here: 
https://www.doc.ic.ac.uk/~ecr05/MSM_HOCR_v2<https://urldefense.proofpoint.com/v2/url?u=https-3A__www.doc.ic.ac.uk_-7Eecr05_MSM-5FHOCR-5Fv2&d=DwMF-g&c=aFamLAsxMIDYjNglYHTMV0iqFn3z4pVFYPQkjgspw4Y&r=FnxR7WKbDxh2At2YW0pY1A&m=CzDp4Ukmm8OuwpwAp9eYjkBN0s8CYTBMIoP_fut4qhA&s=x-zvb7DUgSc7Ck0jE53IXlmoNQSeuA5YIMIg6jL5Zb4&e=>/

Here is the recommended order of pipelines:

  1.  PreFreeSurfer
  2.  FreeSurfer
  3.  PostFreeSurfer (using MSMSulc)
  4.  fMRIVolume
  5.  fMRISurface
  6.  ICA+FIX
  7.  MSMAll (Do MSM Surface Registration)
  8.  GroupDeDrift (Compute and Group drift, can skip if you don’t want to)
  9.  DedriftAndResample (Apply MSMAll)
  10. *Global Noise Removal* (not available publicly yet, but will handle 
residual global noise in the data without removing the global signal)
  11. Resting state analysis

For a resting state analysis, you could do something like dual regression and 
fslnets to make netmats.  You could use the HCP’s multi-modal parcellation to 
parcellate the MSMAll aligned dense timeseries into a parcellated timeseries, 
and then use fslnets  to estimate functional connectivity (can be either full 
correlation or partial correlation—which is better if step 10 has not been 
done).  You can also use the MIGP algorithm to combine resting state fMRI data 
across subjects for group ICA or group dense functional connectivity.  You can 
use wb_command -cifti-correlation to compute functional connectivity.

Peace,

Matt.

From: 
<[email protected]<mailto:[email protected]>>
 on behalf of "Fales, Christina L" 
<[email protected]<mailto:[email protected]>>
Date: Friday, June 30, 2017 at 12:30 PM
To: "'[email protected]<mailto:'[email protected]>'" 
<[email protected]<mailto:[email protected]>>
Cc: "Fales, Christina L" <[email protected]<mailto:[email protected]>>
Subject: [HCP-Users] Resting State processing

Hi HCP gurus:
I’ve been trying to adapt the HCP pipeline for use in our group, and having 
trouble with the tools for resting state processing. The pipeline’s Example 
programs are super helpful for illustrating calls to the minimal preprocessing 
and the Task-fMRI tools. However the resting-fMRI tools are organized 
differently, with no example calling program provided. I wonder if I could get 
a few tips?
I am using pipeline version v3.22.0-beta.2, and I have so far successfully run 
pipeline modules on HCP subjects as well as our own:
PreFreesurferPipeline.sh
FreesurferPipeline.sh
PostFreesurferPipeline.sh
GenericfMRIVolumeProcessingPipeline.sh
GenericfMRISurfaceProcessingPipeline.sh
ICA-FIX
I know that after ICA-Fix I could continue with a group analysis using Dual 
Regression and FSLnets. But how to proceed if one wanted to do a seed-based 
analysis? I’m not sure I see the purpose of PostFix, ReApplyFix and 
RestingStateStats. They rely on compiled matlab code, so it is hard to figure 
out what they are actually doing.
Regardless, I tried running RestingStateStats, but it triggered an error when 
it could not find a file apparently created by MSMSulc. (I assume this is 
because I ran earlier parts of the pipeline with RegName=”FS”). When I tried to 
rerun PostFreesurferPipeline.sh with RegName=”MSMSulc”, it seems that our 
version of the pipeline does not include an MSM binary. I have searched the HCP 
website but don’t see where this binary is available.  Alternatively, if I 
download the available MSMAll, can it be used with pipeline version 3.22?
Unfortunately with all of the excellent documentation on the HCP website, there 
is a dearth of *high-level* guidance on how to proceed with resting-state 
processing. I’d be grateful for any insights…
Thanks,
Christina Fales

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Sally Durgerian
Neurolab G2415
Medical College of Wisconsin
8701 W. Watertown Plank Rd.
Milwaukee WI 53226








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