The variance normalization is per timeseries.  We prefer to use the _vn files 
provided by the RestingStateStats pipeline so that this is equalizing the 
unstructured noise.

Peace,

Matt.

From: HERACLES PANAGIOTIDES <he...@uw.edu<mailto:he...@uw.edu>>
Date: Saturday, December 30, 2017 at 2:05 PM
To: Matt Glasser <glass...@wustl.edu<mailto:glass...@wustl.edu>>
Subject: Re: [HCP-Users] (no subject)

Hello Matt,

I am getting ready to launch a group analysis of rfMRI files using Matlab.  I 
want to make sure that I am not making any fundamental errors in preprocessing. 
 I would be deeply appreciative, if I could (phone?) consult with you or anyone 
else, to make sure that I am not making any gross mistakes.  At this point, I 
am following your instructions about mean and and variance normalization before 
ROI extraction.  For example, is this equivalent to a z-score transformation?  
If so, is this done to the entire 4D volume or to the individual voxel time 
series?

At any rate, these are some of my questions.

Thank you for being so kind.

Heracles


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