Why do you need smoothing if you are using ROIs? If you smooth in the volume you will be mixing in CSF, white matter, and cortex from the opposite banks of gyri and sulci. Even smoothing on the surface will mix signal between different cortical areas and isn’t needed if you are doing an ROI analysis.
Peace, Matt. From: <[email protected]<mailto:[email protected]>> on behalf of David Hofmann <[email protected]<mailto:[email protected]>> Date: Tuesday, May 29, 2018 at 4:24 PM To: hcp-users <[email protected]<mailto:[email protected]>> Subject: [HCP-Users] Additional smoothing of FIX extended resting state data? Dear all, as far as I read in previous posts on the list, spatial smoothing of the volumetric resting state data is not recommended. But this was with regard to group ICA. Would you also recommend not to apply any further spatial smoothing for the (volumetric) resting state data, when running ROI-based (group) analysis on multiple subjects? Comparing the results of smoothed (4,6, FWHM) and unsmoothed data gives highly different results in my case, so I'm a bit confused now. greetings David _______________________________________________ HCP-Users mailing list [email protected]<mailto:[email protected]> http://lists.humanconnectome.org/mailman/listinfo/hcp-users _______________________________________________ HCP-Users mailing list [email protected] http://lists.humanconnectome.org/mailman/listinfo/hcp-users
