Hi - a while back I had a lot of success using workbench in a study of
tractography and anatomy. I seeded tractography from the midthickness
cortical surface of mostmortem macaque data. Then I used

wb_command-convert-matrix4-to-workbench-sparse

and

wb_command -convert-matrix4-to-matrix2

to get a matrix of gray matter vertices to white matter voxels, and
also to get trajTEMP.wbsparse files from gray matter ROI to display
visually in workbench.

This is straigtforward using surfaces as seeds. Now I want to
expand this analysis to entities within the white matter, i.e. fiber
budles.

I want to seed from a set of voxels, and then make a
trajTEMP.wbsparse. That would be the start, in general I want to
implement, expand and enrich the ideas here
https://elifesciences.org/articles/35237.

convert-matrix4-to-workbench-sparse will take voxels as seeds. What I
need is a matrix of seed voxels by brain voxels instead of vertices by
voxels.

But to make this I need a cifti template. There is no way to generate
one using wb_command that I can see.

I think I need to make this using the matlab code on github, and the
cifti specification. But I am finding it very challenging to do this.

Is there any kind of tutorial, or gentle documentation on this?

best wishes

Colin

Colin Reveley
Neuroecology and Anatomy lab
Wellcome Centre for Integrative Neuroimaging
Centre for Functional MRI of the Brain (FMRIB)
Nuffield Department of Clinical Neurosciences
John Radcliffe Hospital
University of Oxford
John Radcliffe Hospital
University of Oxford

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