You might cross-post this on the FSL list as well. The approach seemed okay, though I’m not sure I would do that if I was trying to do something similar. Not sure what I would do.
Matt. From: <[email protected]<mailto:[email protected]>> on behalf of Amin Dadashi <[email protected]<mailto:[email protected]>> Date: Monday, July 30, 2018 at 7:46 AM To: hcp-users <[email protected]<mailto:[email protected]>> Subject: [HCP-Users] Seed-based tractography group analysis Dear HCP experts, I want to perform a seed-based (preferably probabilistic) tractography for some brainstem ROIs using the HCP 7T DTI dataset. To do so, I used FDT probtrackx2 for every subject to calculate the ROIs streamlines. In order to do a group analysis (replicating the method here<http://dbic.dartmouth.edu/wiki/index.php/Diffusion_Tensor_Imaging_Analysis#Combining_Individuals_into_a_Group>), I created a binary pathways mask by puting the threshold#1 on each individual probabilistic map "fdt_paths.nii.gz". Then, I chose the threshold#2 for the summation of the individuals' binarized connectivity map to find the most recurring streamlines among subjects. The value of each "fdt_paths.nii.gz" voxel shows the accumulative number of streamlines from all the voxels under the ROI mask. Now, the issue is how to choose threshold#1, which is probably dependent on many factors; specifically the tracts length (and also maybe seeds location and volume?...). And a more basic question is if this whole approach makes sense at all, since no inferential statistics is being used? Thank you in advance. Best, Amin _______________________________________________ HCP-Users mailing list [email protected]<mailto:[email protected]> http://lists.humanconnectome.org/mailman/listinfo/hcp-users ________________________________ The materials in this message are private and may contain Protected Healthcare Information or other information of a sensitive nature. If you are not the intended recipient, be advised that any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this email in error, please immediately notify the sender via telephone or return mail. _______________________________________________ HCP-Users mailing list [email protected] http://lists.humanconnectome.org/mailman/listinfo/hcp-users
