I would recommend running the multi-run FIX pipeline for that on all the fMRI 
data together.  That works on the volume data and then also cleans the CIFTI 
data at the same time.

Matt.

From: 
<hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>>
 on behalf of Leonardo Tozzi <lto...@stanford.edu<mailto:lto...@stanford.edu>>
Date: Tuesday, January 8, 2019 at 11:35 AM
To: "hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>" 
<hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>>
Subject: [HCP-Users] Identifying noise components in group MELODIC on ciftis

Dear experts,

I have preprocessed with the minimal preprocessing pipeline some data which 
includes resting state and 3 fMRI tasks. I have then ran MELODIC group ICA on 
the resulting dtseries.nii files (for each task separately).
My question is this: I have only greyordinate data in the outputs, so how can I 
optimally identify the noise components since I have no data for example from 
the CSF or white matter? I am also wondering if running the ICA on the 
greyordinate data is already somehow excluding the noise components that are 
predominantly in the CSF and white matter. I was thinking one way I could 
proceed is to use the statistics produced from MELODIC of the comparison 
between the components and the “background noise” (although I am unsure about 
how this is defined) and/or enter the GLMs of my tasks in MELODIC and see if I 
find components that correlate with the design (but then I would not know what 
to do with resting state).
Another possibility would be to use the FIX pipeline, but I am not sure if it’s 
implemented for tasks and if it can be used at the group level. In any case, I 
wanted to make sure that the processing is the same for resting state and task 
data. Also, I would probably need to retrain the classifier, since we are 
conducting our experiment at a different site and on a GE magnet, correct?
I would appreciate any pointers on how to best proceed with this matter.
Thank you very much,

Leonardo Tozzi, MD, PhD
Williams PanLab | Postdoctoral Fellow
Stanford University | 401 Quarry Rd
lto...@stanford.edu<mailto:lto...@stanford.edu> | (650) 5615738


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