Guix already supports cross-compilation out of the box of 32-bit
packages on any architecture:

        guix build --system=i686-linux PACKAGES...

Now the question is: is it possible to run the produced binaries
directly (no VM)?

Many other distributions have support for the so-called "multilibs",
that is, a separate 32-bit library tree with the 32-bit linker
configured to load those instead of their 64-bit counterparts.

Does Guix have any provision for multilibs?

--
Pierre Neidhardt

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