In bone marrow smears it is caused by improper fixation. In the same way that 
Cabot rings in red blood cells are caused by improper fixation with methanol.
René J.

--- On Thu, 2/12/09, Sheila Haas <[email protected]> wrote:

From: Sheila Haas <[email protected]>
Subject: [Histonet] Bone Marrow Smears
To: [email protected]
Date: Thursday, February 12, 2009, 10:12 AM

Hi all. I have a pathologist complaining about "naked" nuclei
in his bone marrow smears. It's fairly random, some are great and
some are "naked". Anyone heard of this and have any idea what
may be causing this nakedness?
Any input would be helpful.Thank you.
 
Sheila Haas
Laboratory Supervisor
Micro Path Laboratories



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