Hello all out there, 
  
This is regarding: Ray Koelling; currently from just north of the Seattle, WA 
area.  If you and I have connected in some way over the last 47 years, the 
following is a message concerning my (semi)-retirement that I hope you will 
enjoy and anyone with little or no interest in such writing or that knows me 
not, can easily use the delete button right now to save themselves a few 
minutes of OT reading. 
  
It is time in life to shift a bit of focus after this long and amazing anatomic 
pathology journey.  There was the high school summer job in the mid 60's at a 
St. Louis histopath lab changing a Lipshaw linear, open air tissue processor 
(we used dioxane both miscible with aqueous solutions and paraffin and NOT the 
dioxin of Agent Orange infamy) along with folding A LOT of paper boats for 
embedding and making 10% formalin from 55 gallon drums of 37% formaldehyde 
solution.  Somehow my brain has survived relatively unscathed.  Some may 
dispute that last sentence.  Working at Jackson Memorial Hospital in South 
Florida with the great Dr. Azorides Morales and Dr. Mehred Nadji (actually 
Nadji was a resident when I was there and I have a treasured picture of him 
kicked back at a BBQ at my house wearing his famous sandals).  To learning more 
advanced immunology, histology and a lot more of cellular/molecular techniques 
along with the ability to critically think during the 5 years (of both 
unbelievably positive heaven and unrelenting, unforgiving hell) of graduate 
school.  To the biotechnology world and working on such drugs as etanercept, 
panitumumab, denosumab and (still in testing) TSLP, a compound that I had 
actually worked on in graduate school but when it was the newly discovered 
murine form TSLP and then also 50 other discovery molecules that all saw their 
shelving at various stages of development as failed candidates to progress in a 
particular pathway.  To then being able to work with Dr. Allen Gown in his 
fantastic lab in the Seattle area.  So if we have run into one another, in 
person, on-line, at a meeting or anywhere in the last nearly half century, hope 
you are doing well and are keeping safe and I wish you the best. 
  
A part of my time now is going to be spent on some K-12 education projects.  
Organizing and helping at 2 different school districts for district-wide 
science fairs and STEM (science, technology, engineering, math) career 
festivals.  I am helping at the annual biotechnology fair in the Puget Sound 
Region for 300-400 high schoolers.  And am on Board of the Washington State 
Science and Engineering Fair that is the entrance point for this state into the 
big International Intel Science Fair.  Why?  It is no new, great news flash at 
all that the US is sinking further behind many countries of the world in math 
and science education.  And that is to the severe, possibly life-long detriment 
of kids now who will be less able to compete, as adults, with a global economy, 
jobs and society of the 21st century and which will frankly revolve a lot 
around STEM issues whether you like it or not.  The world is simply not now, 
nor will ever be again, as it was with me holding a 4-year degree in 
biology/chemistry in 1973 and at that time having virtually unlimited access to 
whatever I wanted to do. 
  
Then for those kids K-12 who don't like math and science at all and don't want 
to be in STEM or any kind of STEM career I have offered up this message to 
them.  Not liking STEM as a career is perfectly fine.  You need to do in your 
life what your talents and dreams allow you to do.  Yet remember this.  No 
matter what non-STEM thing you do in life, you as a voting, tax-paying, living, 
breathing adult will be surrounded by STEM issues all throughout life.  You 
will be voting for/against issues or policies and for/against politicians and 
some, even many of those issues are STEM issues.  Radioactive storage waste in 
salt domes in Nevada?  Fracking in the upper Midwest?  Coal vs. nuclear vs. 
"green energy" anywhere?  5 cent plastic bags to cure global warming?  
Healthcare?  Genetically modified foods?  Embryonic vs. other stem cell 
research?  Aging populations?  Disease?  Mars yes or Mars no?  End-of-life 
issues?  Steroids and other drugs in the environment and food stuffs?  Sonar 
testing in oceans? 100 other politically driven STEM-related issues.  How do 
adults now, and then you eventually when older, get your "science" information? 
 Journalists (on both sides of the political divide) see themselves as having a 
higher-level moral obligation to now fine-tune and manipulate the news, 
including science news, instead of just reporting it.  Politicians (on both 
sides of the political divide) spew out any so-called "science" if it gets them 
more votes than they loose.  Talk show hosts (on both sides of the political 
divide) spew out "science" if it gets them more ratings than they loose.  
Self-promoting, mainly amateurish-science bloggers or tweeters (on both sides 
of the political divide) spew out "science" news to appease their own 
narcissistic proclivities. 
  
So no matter what you do in life, you will be in a world of STEM and do you 
want to think and act rationally and knowledgeably about such issues for the 
positive benefit of a human society or do you want to advocate for/against or 
vote for/against something related to STEM issues based upon purely emotional, 
knee-jerk, thoughtless ideology (from both sides of the political divide)?  You 
can see what a horribly, messy state of affairs that later path has brought us 
to in this society.  So that is my message to the K-12 to use your brain, the 
most powerful computer ever invented, to THINK.  And why I'm  trying to do some 
of the things now and that I think I'll have fun with using my career acquired  
knowledge with and in addition hopefully do a little good along the way for the 
next generation.  No one will ever convince me that learning, or at least being 
exposed to, fundamental scientific principles and fundamental scientific 
thought processes, won't actually help anyone in almost all facets of their 
life and in decision making. 
  
Of course there are also yard-chores, making dinner, golf, hurling, the 
accordion, re-learning my German, writing 2 books, genealogy research in 
Southern Germany and the Alsace-Lorraine region during a future trip, 
weight-training, Senior Olympics, doing the top of Mt. Fuji hike before too 
long, trip to New Zealand to see where the Hobbit/LOTR trilogy was made, etc. 
and even a few other various things I'm sure I'll find to keep me busy. 
  
Best of luck to all, even if you deleted this message long ago to gain a bit of 
time.  I'll be still monitoring the HistoNet and maybe even throwing in my 
2-cents about technical/scientific issues only, if I think I have something 
useful and appropriate to share.  Keep in touch. 
  
Ray (Koelling) 
Lake Forest Park, WA 
  
  
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