Hi Patty,

We did some of these in paraffin in my other life in Kansas City. Essentially 
for these we processed them in paraffin, and would embed them in Ls, letting 
gravity do what it does best. We would line them up side by side, as 
perpendicular to the edge as we could. We had a stereomicroscope attached to an 
arm so we could see what we were doing with the small samples, and would use 
either a toothpick, wooden stick, or very fine brush to orient them in the 
embedding L. If we needed transverse sections, we would just mount the block as 
such in a standard specimen clamp and section. Honestly for us it was much 
quicker than using plastics, and it gave us the ability to do regular specimen 
and IHC stains on them if needed.

Teri Johnson
Manager, Histology
Genomics Institute for
Novartis Research
Foundation
San Diego, CA
858-332-4752

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