Eosin can be a problem in IHC as well especially if you use alk phos red 
detection.

Patsy Ruegg, HT(ASCP)QIHC
Ruegg IHC Consulting
40864 E Arkansas Ave
Bennett, CO 80102
H 303-644-4538
C 720-281-5406
[email protected]



> From: [email protected]
> To: [email protected]
> Date: Wed, 14 Jan 2015 22:56:51 +0000
> Subject: Re: [Histonet] marking small samples
> CC: [email protected]; [email protected]
> 
> I've been told Eosin affects a lot of molecular testing. We used to use it in 
> our process but discontinued to not interfere with future testing.  
> 
> Sent from my iPhone
> 
> > On Jan 14, 2015, at 5:31 PM, "Morken, Timothy" <[email protected]> 
> > wrote:
> > 
> > We use eosin the processor alcohol. Also we use blue-tinted paraffin which 
> > helps with contrast on small bx
> > 
> > Tim Morken
> > Supervisor, Histology, Electron Microscopy and Neuromuscular Special Studies
> > UC San Francisco Medical Center
> > San Francisco, CA
> > 
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> > 
> > -----Original Message-----
> > From: [email protected] 
> > [mailto:[email protected]] On Behalf Of Yves 
> > Heremans
> > Sent: Wednesday, January 14, 2015 2:03 PM
> > To: [email protected]
> > Subject: [Histonet] marking small samples
> > 
> > Dear Histonetters,
> > 
> > Does anyone know of a good method to mark (stain) small samples (tissue or 
> > cells) prior to paraffin embedding to aid in finding back more easily the 
> > sample in the paraffin block ?
> > Preferably something that would not interfere with subsequent antibody 
> > staining.
> > 
> > Yves
> > 
> > 
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