Dear Vladimir,

Thank you for sharing your considerations.

I must have misrepresented my position in the rush to ask my questions.

My intention was to cover what you state as being important under 
'retrodiction', and it *is* the primary scientific justification I will 
be putting forward for the project. More, the monograph in question fits 
your description of the type of article you would want addressed, I believe.

My questions were about existing big formalizations, not so much what I 
had done.

Cheers,
Rene

On 2/3/14, 11:18 PM, Vladimir Voevodsky wrote:
> Let me express my opinion which is somewhat against what you say.
>
> I would be very interested in seeing the results of a project aimed at 
> rigorous formalization of all levels of reasoning in a relatively small 
> scientific paper which involves experiment(s). May be one of the classic 
> papers in biology.
>
> I think achieving such a goal is highly non-trivial, visionary and  important 
> undertaking.
>
> I would be much less interested in seeing the results of a project which 
> would formalize a large monograph in the ``industrial" style i.e. without 
> paying attention to the new ideas which arise in the process and aiming only 
> at obtaining the final result.
>
> Vladimir.
>
>
>
>
> On Feb 2, 2014, at 11:09 PM, Rene Vestergaard <[email protected]> wrote:
>
>> I will shortly be attempting to reach a, for us, non-standard audience with 
>> a project that includes the verification of the complete reasoning in a 
>> molecular-biology monograph.
>>
>> The primary sales argument is by proxy: there’s a Curry-Howard component to 
>> the project that allows us to solve an open problem in the application 
>> domain.
>>
>> The primary scientific argument concerns formal reasoning, including the 
>> value of formalising/verifying a large body of knowledge, be it a textbook, 
>> a monograph, a “big” result, or similar.
>>
>> I have my own personal arguments for why large applications are a good idea:
>> - tests of and guidance for maturity/naturalness/expressivity of tools and 
>> methodologies,
>> - development of libraries/momentum/etc.,
>> - teaching/industrial/etc. purposes,
>> - retrodiction and, of course,
>> - assuring large case splits and proof by reflection.
>>
>> I was hoping people would help me with
>> 1) what big applications have been done? what arguments were used?
>> 2) do the arguments hold up in retrospect?
>>
>> While 1) can be answered by references, I am particularly hoping that some 
>> of the people behind these projects would attempt to answer 2) as best as 
>> possible.
>>
>> Cheers,
>> Rene
>

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