Here is my configuration

1)server
Imail 803 - registry - killerwebmail 4.0 (images serve from IIS40)- No
antivirus - Spamming control on(10 server in the list) - incoming rules -
install on D drive - 100 Domains - +/- 5000 mailboxes.
Pentium 3 750 Mhz - 512 Mb Ram - nt4 sp6a + all latest patches - Microsoft
DNS Server
No performance issue - running stable - no reboots unless for patching nt40.

2)server
Imail 803 - SQL2000 Database (same server) - killerwebmail 4.0 (images
server from IIS50) - No antivirus - Spamming control on(10 server in the
list) - incoming rules - install on D Drive - 100 Domains - +/- 5000
Mailboxes
Dual Pentium 3 500 Mhz - 1 GB Ram - nt4 sp6a + all latest patches -
Microsoft DNS Server.
No Performance issue - running stable - no reboots unless for patching nt40.

We notice well a loss of performance with the webmail. 

Hope this will help


Miguel Jamous
email: [EMAIL PROTECTED]


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