I just spoke with Panda and they even have a nice white paper about using their software. The BIG problem with it is that they want $3 per mailbox per year to use it!
... or, you can use their desktop client along with another virus scanner and Declude Virus Pro, and get the best of two virus scanners. If you've got 5,000 users, that's less than $.30/user upfront, and less than $.10/user annually.
-Scott
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