http://www.hindustantimes.com/StoryPage/StoryPage.aspx?sectionName=HomePage&id=5dabd328-1dc3-4438-a11b-8b4d81300bbd&Headline=Tribute-to-a-truly-inspired-mind

Tribute to a truly inspired mind
EnlargePTI
Former President APJ Abdul Kalam addresses at the concluding day of National 
summit on 'National value crisis and redressal' in New Delhi on Wednesday.

Dr APJ Abdul Kalam, Hindustan Times
August 15, 2009
First Published: 02:51 IST(15/8/2009)
Last Updated: 03:07 IST(15/8/2009)

 
I am happy that Hindustan Times has brought out the India Inspired series 
showcasing innovations and creative thinking, which can transform the lives of 
many in the country.

Such innovative spirit has to become a part of life of every young mind in the 
nation. I would like to present to the readers two great minds who have 
nurtured creativity and innovation even in the most difficult circumstances and 
both of them are remembered for their work.

Birth of Creativity in a difficult situation Mario Capecchi had a difficult and 
challenging childhood. For nearly four years, Capecchi lived with his mother in 
a chalet in the Italian Alps.

When World War II broke out, his mother, along with other Bohemians, was sent 
to Dachau as a political prisoner. Anticipating her arrest by the Gestapo, she 
had sold all her possessions and given the money to friends to help raise her 
son on their farm.

On the farm, he had to grow own wheat, harvest; take it to miller to be ground. 
Then, the money which his mother left for him ran out and at the age of four 
and half years, he started sometimes living in the streets, sometimes joining 
gangs of other homeless children, sometimes living in orphanages and most of 
the time hungry.

He spent the last year in the city of Reggio Emelia, hospitalised for 
malnutrition where his mother found him on his ninth birthday after a year of 
searching. Within weeks, Capecchi and his mother sailed to America to join his 
uncle and aunt.

He started third grade afresh and studied political science. But he didn't find 
it interesting and changed into science, became a mathematics graduate in 1961 
with a double major in Physics and Chemistry.

Although he really liked Physics, its elegance and simplicity, he switched to 
molecular biology in graduate school, on the advice of James D Watson, who 
advised him that he should not be bothered about small things, since such 
pursuits are likely to produce only small answers.

His objective was to do gene targeting. The experiments started in 1980 and by 
1984, Capecchi had clear success.

Three years later, he applied the technology to mice. In 1989, he developed the 
first mice with targeted mutations. The technology created by Doctor Capecchi 
allows researchers to create specific gene mutations anywhere they choose in 
the genetic code of a mouse. By manipulating gene sequences in this way, 
researchers are able to mimic human disease conditions on animal subjects. What 
the research of Mario Capecchi means for human health is nothing short of 
amazing, his work with mice could lead to cures for Alzheimer's disease or even 
Cancer. The innovations in genetics that Mario Capecchi achieved won him the 
Nobel Prize in 2007. The message we learn from Mario Capecchi:

"When you wish upon a star, Makes no difference who you are Anything your heart 
desires Will come to you"

A genius well ahead of his time, Ramanujan, born and raised in Erode, Tamil 
Nadu, first encountered formal mathematics at the age of 10. He demonstrated a 
natural ability at mathematics, and was given books on advanced trigonometry by 
SL Loney.

He mastered this book by age thirteen, and even discovered theorems of his own. 
He demonstrated unusual mathematical skills at school, winning many awards.

By the age of seventeen, Ramanujan was conducting his own mathematical research 
on Bernoulli numbers and the Euler-Mascheroni constant. He received a 
scholarship to study at Government College in Kumbakonam. He failed his 
non-mathematical coursework, and lost his scholarship. Srinivasa Ramanujan 
lived only for 33 years and did not have formal higher education or means of 
living.

Yet, his inexhaustible spirit and love for his subject made him contribute to 
the treasure house of mathematical research - some of which are still under 
serious study and engaging allavailable world mathematicians' efforts to 
establish formal proofs.

Ramanujan was a unique Indian genius who could melt the heart of the most 
hardened and outstanding Cambridge mathematician Prof G H Hardy. In fact, it is 
not an exaggeration to say that it was Professor Hardy who discovered Ramanujan 
for the world. Professor Hardy rated various geniuses on a scale of 100.

While most of the mathematicians got a rating of around 30 with rare exceptions 
reaching to 60, Ramanujan got a rating of 100. There cannot be any better 
tribute to either Ramanujan or to Indian heritage. One of the tributes to 
Ramanujan says that, 'every Integer is a personal friend of Ramanujan'.

Ramanujan used to say "An equation means nothing to me unless it expresses a 
thought of God". For him the understanding of numbers was a process of 
spiritual revelation and connection.

In his investigations into pure mathematics, he drew extraordinary conclusions 
that mystified his colleagues, but were usually proven, eventually, to be 
right. He opened a universe of theory that still today is reaping applications. 
The landscape of the infinite was to Ramanujan a reality of both mathematics 
and spirit. 

Dear readers you saw, how great innovative minds even in difficult 
circumstances, challenged the problems to succeed through the instrument of 
knowledge and creativity.

Dear readers, when I we see the great lives of Mario Capecchi and Ramanujan, 
very important traits emanate for achievements are: Inventions and discoveries 
have emanated from creative minds that have been constantly working and imaging 
the outcome in the mind. With imaging and constant effort, all the forces of 
the universe work for that inspired mind, thereby leading to inventions or 
discoveries. Higher the number of creative minds in the country, the best 
results of innovation in all the three sectors of the economy will emerge.

Inventions and discoveries is possible only through inspired minds. Inspired 
minds will elevate the nation in thinking and action.. May I wish the people of 
our nation a happy, prosperous, peaceful and dynamic life. On this independence 
day, let us all take the independence day oath:

"My national Flag flies in my heart and I will bring glory to my nation".


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