http://www.smh.com.au/world/mexican-researchers-patent-heroin-vaccine-20120227-1tx3m.html

Mexican researchers patent heroin vaccine 
February 27, 2012 - 7:13AM 
  a.. 
 
Breakthrough ... Maria Elena Medina speaks about the patent of a new vaccine 
that could reduce addiction to heroin. Photo: Reuters

While Mexico grapples with relentless drug-related violence, a group of Mexican 
scientists is working on a vaccine that could reduce addiction to one of the 
world's most notorious narcotics: heroin.

Researchers at the country's National Institute of Psychiatry say they have 
successfully tested the vaccine on mice and are preparing to test it on humans.

The vaccine, which has been patented in the United States, works by making the 
body resistant to the effects of heroin, so users would no longer get a rush of 
pleasure when they smoke or inject it.

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"It would be a vaccine for people who are serious addicts, who have not had 
success with other treatments and decide to use this application to get away 
from drugs," the institute's director Maria Elena Medina said on Thursday.

Scientists worldwide have been searching for drug addiction vaccines for 
several years, but none have yet been fully developed and released on the 
market.

One group at the US National Institute on Drug Abuse has reported significant 
progress in a vaccine for cocaine.

However, the Mexican scientists appear to be close to making a breakthrough on 
a heroin vaccine and have received funds from the US institute as well as the 
Mexican government.

During the tests, mice were given access to deposits of heroin over an extended 
period of time. Those given the vaccine showed a huge drop in heroin 
consumption, giving the institute hope that it could also work on people, 
Medina said.

Kim Janda, a scientist working on his own narcotics vaccines at the Scripps 
Research Institute in La Jolla, California, said that based on some earlier 
research papers he had read, the Mexican vaccine could function but with some 
shortcomings.

"It could be reasonably effective but maybe too general and affect too many 
different types of opioids as well as heroin," Janda said.

Mexico, a major drug producing and transit country for drugs smuggled into the 
United States, has a growing drug addiction problem. Health Secretary Jose 
Cordoba recently said the country now has some 450,000 hard drug addicts, 
particularly along the trafficking corridors of the US border.

Mexican gangsters grow opium poppies in the Sierra Madre mountains and convert 
them into heroin known as Black Tar and Mexican Mud, which are smuggled over 
the Rio Grande.

Every year, the heroin trade provides billions of dollars to gangs like the 
Sinaloa Cartel and the Zetas. Since 2006, cartel violence has claimed the lives 
of over 47,000 people in Mexico.

Reuters


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