Ref_ Bagaimana dengan keadaan Asthma di NKRI normal, meninkat, menurun atau  
samasekali tidak ada?

http://news.kuwaittimes.net/2012/12/22/number-of-kuwaitis-with-asthma-continues-to-soar/

Number of Kuwaitis with asthma continues to soar 
KUWAIT: Kuwait doctors are warning of a continual rise in the number of 
patients suffering from asthma, a disorder that causes the airways of the lungs 
to swell and narrow, leading to shortness of breath, chest tightness, and 
coughing, estimating that prevalence has risen to approximately 17 percent of 
the population. A recent global asthma prevalence study published this year 
found that global prevalence rates of doctor diagnosed asthma, clinical/treated 
asthma and wheezing in adults were 4.3 percent, 4.5 percent and 8.6 percent 
respectively. Commenting on the sidelines of the Middle East Asthma and Allergy 
meeting (MEAAM) taking place 21 – 22 December in Dubai where local, regional 
and international experts are meeting to discuss asthma management and 
treatment, Dr Ali Alenizi, Head of Department for Allergic Diseases at Al 
Rashed Allergy Clinic in Kuwait, commented that the figure is continuing to 
surge ahead of global prevalence. The annual cost of treating a case of 
moderate asthma in Kuwait is $562, while deaths attributed to the disease can 
be traced to a number of factors including an underestimation of its severity, 
delayed treatment in acute episodes, and unsatisfactory management.

The same study mentions that Kuwait ranks 13thamong 65 countries in the 
prevalence of symptoms of asthma in children, with a prevalence of current 
wheeze of 16 percent amongst Kuwaiti children – higher than other countries in 
the Arab world where similar surveys were conducted such as Oman, Morocco and 
Lebanon. Studies also show that many patients with asthma remain poorly treated 
when symptoms of asthma worsen. Anecdotal evidence also suggests that as many 
as half of the patients diagnosed with asthma are not controlled properly 
according to Dr Alenizi, a number reflected in other parts of the Middle East. 
Dr Bassam Mahboub, Vice President of the Emirates Allergy and Respiratory 
Society, estimates that around 13 percent of the UAE population lives with the 
disorder that causes the airways of the lungs to swell and narrow, leading to 
wheezing, shortness of breath, chest tightness and coughing. “One of the 
biggest problems is that there is a perceived lack of need for medication until 
symptoms occur, and then patients rush to the emergency department because the 
symptoms, such as shortness of breath, are frightening – this creates 
unnecessary stress on the patient and also an unnecessary burden on emergency 
resources,” commented Dr Mahboub.

Approximately 60 percent of asthma patients suffer from allergic asthma, and 
concerning for local doctors is the 10 percent of asthma patients that suffer 
from severe persistent allergic asthma that are not adequately controlled by 
conventional therapies – the consequences for the lack of control in the 
patients could result in death, according to the author of a new local study on 
the disease. “There have been recent advancements in the treatment of 
uncontrolled severe persistent allergic asthma in the form of a monoclonal 
anti-IgE antibody, omalizumab. We found that over the course of four years, 83% 
of the patients we treated with omalizumab had significant clinical improvement 
in their asthma control – which is very promising,” said Dr Wagih Djazmati, 
Consultant and Head, Respiratory Division, SKMC, who is presenting the findings 
of his new study at the MEAAM. Omalizumab works by binding to IgE – a natural 
substance found in the body – thus preventing it from binding to mast cells, 
and consequently the release of mediators that can cause inflammation is 
stopped. “Severe asthmatics require regular and multiple treatments, and 
monitoring, and while I recommend to asthmatics that they come in to see me 
every three to six months, I need to see patients with severe asthma every 
month as the disease is extremely unpredictable and needs regular monitoring, 
particularly in uncontrolled patients,” said Dr Mahboub.

Asthma is caused by inflammation in the airways, and when an attack occurs, the 
muscles surrounding the airways become tight and the lining of the air passages 
swells, reducing the amount of air that can pass by. An attack can be triggered 
by animals, changes in weather, dust and tobacco smoke – of particular concern 
to the region. “Around 20 to 25 percent of asthmatics are smokers, which is 
deeply troubling as smoke can trigger an attack. For this region as well, 
sandstorms and dust mites are prevalent here, and worsen in the humidity – 
which is during most of the year,” added Dr Djamatzi.


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