Hi JC - :)  Thanks for the interesting email !

On 03/07/2018 03:27, Juan Carlos Sanchez wrote:
> I noticed that when having stop sign in an aminoacid sequence “*” ,
> when using MUSCLE web service to realign the sequences it will be
> converted to a gap “-“
Ah - that sounds like Muscle is just treating '*' as a gap.
> I know is not common to align with stops, but in some cases I think it
> happens.It might be an issue of MUSCLE itself, but I thought it could
> be interesting to share this bug here.
What would be the ideal behaviour  ? 

We could, for instance, have Jalview reinsert the '*' in the alignment
that is returned from Muscle...

Jim.

-- 
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Dr JB Procter, Jalview Coordinator, The Barton Group
Division of Computational Biology, School of Life Sciences
University of Dundee, Dundee DD1 5EH, UK.
+44 1382 388734 | www.jalview.org | www.compbio.dundee.ac.uk

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