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From: PlusNews <[email protected]>
Date: Wed, Apr 13, 2011 at 4:53 PM
Subject: HIV/AIDS: Five ways to improve adherence to ARVs
To: Jean-Francois Darcq <[email protected]>


HIV/AIDS: Five ways to improve adherence to ARVs

NAIROBI, 13 April 2011 (PLUSNEWS) - Antiretroviral treatment has given
millions of people around the world - six million at last count - a
new lease on life. However, less-than-strict adherence undermines the
efficacy of the drugs.

 Some common reasons for failing to stick to ARV regimens include:
side-effects; insufficient food; long distances and high transport
costs to and from drug collection points; forgetting to take them;
stigma and fear of disclosure of one's status and spending time away
from home.

 Adherence is crucial to preventing the huge expense of putting
patients on second- and third-line HIV treatment. Here are some ways
HIV programmes can improve adherence:

 Continuous counselling - Crucial to ensure patients understand the
importance of strictly adhering to their medication and make healthy
lifestyle choices. Many HIV programmes offer counselling at the
initiation of ART, after which patients merely collect their drugs
from the pharmacy monthly, being seen a few times a year or only when
they have other health conditions.

 However, experts recommend sustained ART adherence counselling to
achieve the best results. A randomized controlled study [
http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1000422;jsessionid=168D48D3BB44EBB49E84F177506DB5DA.ambra02
] published in 2011 and conducted in the Kenyan capital, Nairobi,
found that patients who received intensive counselling at the start of
ART were 29 percent less likely to have poor adherence and 59 percent
less likely to have virological failure compared with those who did
not.

 Additional lifestyle counselling, such as alcohol counselling [
http://www.plusnews.org/report.aspx?ReportID=86043 ] for heavy
drinkers, can also improve adherence.

 Community support - Visits by community members to encourage patients
to adhere to their medication, home-based care by community health
workers or people visiting the clinic with the patient and keeping
tabs on them between visits, can all help.

 Some programmes are using community drug distribution to bring health
services closer to remote villages. One Tanzanian project [
http://www.irinnews.org/report.aspx?ReportId=89757 ] uses
community-based volunteers - many of them HIV-positive - and trained
medical workers to drive around villages refilling prescriptions and
providing counselling and support to patients.

 A 2011 South African study [
http://www.ncbi.nlm.nih.gov/pubmed/21259136 ] found community-based
adherence to be crucial in ensuring that patients remained in care,
regularly picked up their treatment and retained low viral loads.

 Task-shifting - Patients do not waste precious working hours and lose
money waiting for medical care. Many African countries lack medical
staff [ http://www.irinnews.org/report.aspx?ReportID=89186 ];
overburdened health workers are unable to provide the proper attention
to patients. Task-shifting - the use of mid- to low-level health
workers rather than doctors to prescribe ART - helps ease the burden
on doctors and saves patients' time.

 As more [ http://www.plusnews.org/Report.aspx?ReportID=91383 ] HIV
programmes take on task-shifting, experts warn that ongoing training
and monitoring [ http://www.plusnews.org/Report.aspx?ReportId=85979 ]
are necessary to ensure the quality of care is not compromised.

 Technology - Many health centres provide patients with devices such
as pill boxes, medical calendars and alarms to help them to remember
to take their drugs at the appropriate time.

 The use of text messages [
http://www.irinnews.org/report.aspx?ReportID=88653 ] to remind
patients to take their medicines and to report health issues to
medical personnel is proving popular and effective. A 2011 study [
http://www.ncbi.nlm.nih.gov/pubmed/21252632 ] of 431 patients at a
rural Kenyan clinic found that 53 percent receiving weekly SMS
reminders achieved adherence of at least 90 percent during the 48
weeks of the study, compared with 40 percent of participants who did
not.

 Social assistance - Patients often abandon their HIV medication due
to hunger [ http://www.plusnews.org/Report.aspx?ReportID=92406 ]; for
others, the costs associated with travelling long distances [
http://www.plusnews.org/report.aspx?ReportID=82881 ] to seek treatment
are simply too high.

 According to a 2010 study [
http://www.aidsrestherapy.com/content/7/1/33 ] in Haiti, food
assistance was associated with improved clinic attendance and
adherence to ART, while a 2010 Ugandan study [
http://retroconference.org/2010/PDFs/831.pdf ] found that cash
transfers of between US$5 and $8 for transport costs resulted in
improved ART adherence and retention in care.

 Researchers [ 
http://www.google.co.ke/url?sa=t&source=web&cd=1&ved=0CB4QFjAA&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F20048268&ei=bIalTbCFCKTu0gG_lPHoCA&usg=AFQjCNFt0u9qhKSIvsLAaJJIJOGNoM6ZXQ
] argue that the cost of food assistance and transportation is dwarfed
by the potential costs - including hospitalization and additional
medication - associated with failure to adhere.

 kr/mw

[END]

This report online: http://www.plusnews.org/report.aspx?reportID=92463



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