Jan wrote:

> Hi Miguel,
> I had some problems posting to the jmol list using two different SMTP
> relays.

I am also having many email problems today.

I am having trouble posting messages to the pdb-l mailing list.


> It is a modified peptide but not at the position where the (lacking) *.O
> should be, but at the *.N as you may see with the LINK record
> http://www.rcsb.org/pdb/docs/format/pdbguide2.2/part_48.html
> LINK CB PYL C1005 N GLY C 5
>
> and there are missing  atoms. REMARK 470 may be considered when the
> monomer class is determined.
> http://www.rcsb.org/pdb/docs/format/pdbguide2.2/part_31.html

I think that it will be much to difficult to parse the REMARK records.

>>> Q: Are there lots of things that can hook on where the carbonyl oxygen
>>> should be?
>>>
>>>
>> The phenylethane group is not "where the oxygen should be" but,
>> rather, attached to the N atom of [gly]5:C.

OK

>>> Q: Do we need to rethink the critera for determing whether or not
>>> something is an AminoMonomer?
>>>
> No, but consider REMARK 470
> or, quick and dirty, we may rethink the criteria where schematic
> rendering could be applied, e.g. where
>  select protein or amino
> is true ('protein' are the determined amino acids and 'amino' the set of
> the standard amino acids)

The only way that we can allow an incomplete residue to participate in a
Polymer is if we relax the requirements for being a Monomer.

But, in this case we need to have the =O because the vector of the
carbonyl group is necessary in order to calculate the plane of the residue
backbone.

>>> Q: What other structures could plug themselves into a protein backbone?
>>>
>>>
>> The question is, to what extent does Jmol have to represent non-real
>> (or extremely exotic) protein-like structures?
>
> no, but as you stated, how to deal with missing atoms and schematic
> rendering.

OK. For now we are going to consider this issue closed.

If someone has a set of specific examples and a recommendation on how to
handle them then we will reopen the issue.


Miguel



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